Respiratory Tract

The respiratory tract is the continuous system of airways that conducts air between the atmosphere and the lungs, enabling gas exchange and serving as a major route for drug delivery. Its nasal passages, bronchi, and smaller airways filter, warm, and humidify inhaled air, while mucus and coordinated ciliary movement remove particles and pathogens. In pharmacology, understanding airway structure, epithelial barriers, airflow, and mucociliary clearance helps determine how inhaled medicines reach target tissues, dissolve, and produce local or systemic effects. This knowledge supports the development and use of bronchodilators, corticosteroids, antimicrobials, and inhalation devices for respiratory disease treatment.

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JoVE Core - Medical-Surgical Nursing
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Anatomy of Respiratory System II: Lower Respiratory Tract

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2025

The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration. The Larynx It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...

Anatomy of Respiratory System I: Upper Respiratory Tract

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2025

The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features. Nose and nasal cavity The nose and nasal cavity represent the main external openings of the respiratory tract.

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JoVE Core - Microbiology

Microbiota of the Respiratory Tract

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2026

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...

Physical Assessment of the Respiratory Tract II: Palpation

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2024

Physical assessment of the respiratory tract is critical in identifying potential health issues. One key component of this assessment is palpation, a technique healthcare providers use to assess the body for abnormalities. This content explores the method of palpation in evaluating the respiratory tract, focusing on thoracic palpation and tactile fremitus. Thoracic Palpation Thoracic palpation detects tenderness, masses, lesions, respiratory excursions, and vocal fremitus. The nurse assesses...

Physical Assessment of the Respiratory Tract II: Inspection

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2024

Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles. Chest Configuration The chest configuration can...

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