Sanity Checks

Sanity checks are quick evaluations used to determine whether a physics calculation, model, or experimental result is physically plausible before accepting it. They work by testing dimensions and units, estimating order of magnitude, examining limiting cases, and checking consistency with conservation laws or known boundary conditions. In physics, these checks can reveal algebraic mistakes, incorrect assumptions, sign errors, or unrealistic parameters without repeating the full derivation. Applied to problems ranging from mechanics and thermodynamics to electromagnetism and quantum systems, sanity checks improve reliability, guide model refinement, and help researchers identify meaningful results that warrant more detailed analysis.

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Education

JoVE Science Education - Clinical Skills

Safety Checks and Ten Rights of Medication Administration

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2015

According to the landmark 1999 Institute of Medicine report To Err is Human: Building a Safer Health System, medication errors are a leading cause of preventable harm and death in hospitals. To mitigate these errors and enhance patient safety, nurses must consistently adhere to the Ten Rights of medication administration. These include the right patient, right medication, right dose, right time, right route, right documentation, right education, right to refuse, right assessment, and right...

Protein Folding Quality Check in the RER

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2023

ER is the primary site for the maturation and folding of soluble and transmembrane secretory proteins. The calnexin cycle is a specific chaperone system that folds and assesses the confirmation of N-glycosylated proteins before they can exit the ER lumen. The primary players of this quality check pipeline are the lectins, ER-resident chaperones, and a glucosyl transferase enzyme. In case the calnexin system in the lumen fails to salvage a misfolded protein, it is transported to the cytoplasm...

Research

JoVE Journal - Neuroscience
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

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Cited by 3 •

2020

The isolated-check visual evoked potential (icVEP) method is implemented here to assess the magnocellular ON pathway that is initially damaged in glaucoma. The study shows standard operative procedures using icVEP to obtain reliable results. It is proved to serve as a useful objective diagnosing technology for the early detection of glaucoma.

Functional Mapping with Simultaneous MEG and EEG

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Cited by 16 •

2010

We use magnetoencephalography (MEG) and electroencephalography (EEG) to map brain areas involved in the processing of simple sensory stimuli.

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

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Cited by 7 •

2017

Based on resting-state functional magnetic resonance imaging with Granger causality analysis, we investigated the alterations in the directed functional connectivity between the posterior cingulate cortex and whole brain in patients with Alzheimer's Disease (AD), patients with Mild Cognitive Impairment (MCI), and healthy controls.

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