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Adattamento del semiautomatico circolanti (CTC) Saggi Tumor Cell per applicazioni cliniche e di ricerca preclinica

Article DOI: 10.3791/51248-v • 14:14 min • February 28th, 2014
February 28th, 2014 •
1,2, 3, 3,4, 1,2,4,5
1London Regional Cancer Program, London Health Sciences Centre, 2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, 3Special Hematology/Flow Cytometry, London Health Sciences Centre, 4Lawson Health Research Institute, 5Department of Oncology, Western University

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Cellule tumorali circolanti (CTC) sono prognostico in diversi tumori metastatici. Questo manoscritto descrive il sistema Gold Standard CellSearch (CSS) CTC piattaforma di censimento e mette in evidenza errori di classificazione comuni. Inoltre, due protocolli adattati sono descritti per l'utente definito caratterizzazione marcatore delle CTC e CTC censimento in modelli murini preclinici di metastasi che utilizzano questa tecnologia.

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Medicina metastasi cellule tumorali circolanti (CTC) sistema CellSearch definito dall'utente caratterizzazione di servirlo, Modello preclinico del mouse la ricerca clinica
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