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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Article DOI: 10.3791/51403-v • 11:12 min • July 16th, 2014
July 16th, 2014 •
1, 1, 2, 2, 2, 2, 2, 1
1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology

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résumé
Automatic Translation

Adaptive deep brain stimulation (aDBS) is effective for Parkinson’s disease, improving symptoms and reducing power consumption compared to conventional deep brain stimulation (cDBS). In aDBS we track a local field potential biomarker (beta oscillatory amplitude) in real time and use this to control the timing of stimulation.

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Adaptive Deep Brain Stimulation Parkinson's Disease Optimization Real-time Fluctuating Disease State Medication State DBS Electrodes Subthalamic Nucleus Local Field Potentials Beta Amplitude Trigger Signal Stimulator Voltage Clinical Efficacy Stabilization Period Motor Function Assessment Unified Parkinson's Rating Scale (UPDRS) Power Consumption Reduction
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