JoVE Journal
Immunology and Infection
Immunology and Infection
Un abonnement à JoVE est nécessaire pour afficher ce contenu.
Chapitres
résumé
Several methods have been described in the literature for modeling bacterial pneumonia in mice. Herein, we describe a non-invasive, inexpensive, rapid method for inducing pneumonia via aspiration (i.e., inhalation) of a bacterial inoculum pipetted into the oropharynx. Downstream methods for assessment of the pulmonary innate immune response are also detailed.