JoVE Journal
Immunology and Infection
Immunology and Infection
Un abonnement à JoVE est nécessaire pour afficher ce contenu.
Chapitres
résumé
This protocol outlines the cefoperazone mouse model of Clostridium difficile infection (CDI) using a clinically-relevant and genetically-tractable strain, R20291. Emphasis on clinical disease monitoring, C. difficile bacterial enumeration, toxin cytotoxicity, and histopathological changes throughout CDI in a mouse model are detailed in the protocol.