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Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Article DOI: 10.3791/55095-v • 08:58 min • January 5th, 2017
January 5th, 2017 •
1, 1, 2, 3, 3, 1
1Department of Molecular Biomedicine, Center for Research and Advanced Studies of the National Polytechnic Institute, 2Department of Physiology, Biophysics and Neurosciences, Center for Research and Advanced Studies of the National Polytechnic Institute, 3Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies of the National Polytechnic Institute

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Current treatments of inflammatory bowel diseases (IBD) aim at alleviating disease symptoms but may cause severe side effects. Thus, alternative strategies are being investigated in animal colitis models. Here, we explain how the beneficial effects of diet supplements on clinical IBD signs are analyzed in such a colitis model.

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Nutritional Supplements Intestinal Epithelial Barrier Functions Experimental Colitis Murine Model Dextran Sulfate Sodium Clinical Science Colitis Model Experiment Low Cost Morphology Analysis Oxidative Stress Neutrophil Recruitment Gavage Administration Esophagus Body Weight Measurement Weight Loss Percentage Stool Sample Collection Guaiac Smear
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