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Bioengineering

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JoVE Journal Bioengineering
Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
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Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells

Article DOI: 10.3791/59094-v • 09:34 min • February 9th, 2019
February 9th, 2019 •
1, 2, 1, 1, 1, 2,3,4, 1
1Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, 2Center for Single Particle Science and Engineering (SPSE), Institute for Molecular Medicine, Health Sciences, University of Southern Denmark, 3Department of Mechanical Engineering and Material Science, Duke University, 4School of Pharmacy, University of Nottingham

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This article describes the encapsulation of falcarindiol in lipid-coated 74 nm nanoparticles. The cellular uptake of the nanoparticles by human stem cells into lipid droplets is monitored by fluorescent and confocal imaging. Nanoparticles are fabricated by the rapid injection method of solvent shifting, and their size is measured with the dynamic light scattering technique.

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Lipid-coated Nanoparticles Falcarindiol Drug Delivery System Cancer Therapy Rapid Injection Method Hydrophobic Drugs Diagnostic Nanoparticles Therapeutic Nanoparticles DLS Nucleation And Growth Physical Chemical Properties Coating Lipids Fabrication Technique Visual Demonstration Drug Delivery To Cells Chloroform Formaldehyde Fume Hood Falcarindiol Stock Solution Sample Concentrator
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