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JoVE Journal Cancer Research
In Vitro del tumore delle cellule Rechallenge per valutazione predittiva della funzione antitumorale chimerico antigene recettore delle cellule T
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In Vitro del tumore delle cellule Rechallenge per valutazione predittiva della funzione antitumorale chimerico antigene recettore delle cellule T

Article DOI: 10.3791/59275-v • 08:04 min • February 27th, 2019
February 27th, 2019 •
1,2, 1, 1, 1, *1, *1
1Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute and Medical Center
* These authors contributed equally

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Qui, descriviamo un metodo di co-coltura in vitro di cellule di T del tumore targeting sfida in modo ricorsivo, che consente analisi fenotipica e funzionale di attività antitumorale delle cellule T.

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Ricerca sul cancro problema 144 immunoterapia trasferimento adottivo di cellule analisi di co-coltura potenza dell'effettore funzione a lungo termine esaurimento delle cellule t
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