Caractériser les mutants liés à la maladie des kinases familiales de la RAF en utilisant un ensemble de méthodes pratiques et réalisables
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July 17, 2019
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Dans cet article, nous avons présenté un ensemble de méthodes pratiques et réalisables pour caractériser les mutants liés à la maladie des kinases de la famille raf, qui comprennent l'analyse in vitro de kinase, l'analyse de co-activation de RAF, et l'analyse de luciferase fractionnée complémentaire.
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Yap, J., Yuan, J., Tee, Z. H., Huang, X., Ng, W. H., Hu, J. Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods. J. Vis. Exp. (149), e59795, doi:10.3791/59795 (2019).
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