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O-ring aortabånd versus tradisjonell tverrgående aortainnsnevring for modellering av trykkoverbelastningsindusert hjertehypertrofi

Article DOI: 10.3791/64455-v • 09:24 min • October 6th, 2022
October 6th, 2022 •
1, 1, 2, 1, 1, 1, 2, 2, 1
1Department of Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck, 2Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Heidelberg, Partner Site Heidelberg/Mannheim

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Denne protokollen beskriver en ny teknikk for aortabånd hos mus for å indusere trykkoverbelastning hjertehypertrofi. For bånd brukes en gummiring med fast indre diameter. Denne nye teknikken lover mindre varians og mer reproduserbare data for fremtidige eksperimenter.

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