Erratum: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease

330 צפיות

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DOI:

10.3791/6500

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20 במאי 2022

במאמר זה

סיכום

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

תקציר

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

The first sentence of the Introduction was updated from:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,00,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

to:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,000,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

Step 1.3 in the Protocol was updated from:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol was used.

to:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol/saline was used.

פרוטוקול

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

The first sentence of the Introduction was updated from:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,00,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

to:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,000,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

Step 1.3 in the Protocol was updated from:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol was used.

to:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol/saline was used.

גילויים

No conflicts of interest declared.

הדפסות חוזרות והרשאות

גלה מאמרים נוספים

מודל למחלת קרוהןקוליטיס מושרית TNBSפתוגנזה של עקה מכניתמודל למחלות מעי דלקתיות במכרסמיםמחלה דלקתית של המעיהכנת תמיסת TNBSתערובת אתנול ומלחמינון לפי משקל גוףדלקת בדרכי העיכולניתוח דלקת טרנסמורלית