Bioinspired Hydroxyapatite
Bioinspired Hydroxyapatite - Related Videos
05:41
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
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Cited by 18 •
2017
This paper describes a novel method for the rapid manufacture of high quality bioinspired nanoscale hydroxyapatite. This biomaterial is of great significance in the manufacture of a wide range of innovative medical devices for clinical applications in orthopedics, craniofacial surgery and dentistry.
13:46
Separation of Single-stranded DNA, Double-stranded DNA and RNA from an Environmental Viral Community Using Hydroxyapatite Chromatography
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Cited by 5 •
2011
We describe an efficient method to separate single-stranded DNA, double-stranded DNA and RNA molecules from environmental viral communities. Nucleic acids are fractionated using hydroxyapatite chromatography with increasing concentrations of phosphate-containing buffers. This method permits the isolation of all viral nucleic acid types from environmental samples.
08:24
Bioinspired Soft Robot with Incorporated Microelectrodes
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Cited by 9 •
2020
A bioinspired scaffold is fabricated by a soft photolithography technique using mechanically robust and electrically conductive hydrogels. The micropatterned hydrogels provide directional cardiomyocyte cell alignment, resulting in a tailored direction of actuation. Flexible microelectrodes are also integrated into the scaffold to bring electrical controllability for a self-actuating cardiac tissue.
08:04
Preparation of Functional Silica Using a Bioinspired Method
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Cited by 13 •
2018
Here, we present a protocol to synthesize bioinspired silica materials and immobilize enzymes therein. Silica is synthesized by combining sodium silicate and an amine 'additive', which neutralize at a controlled rate. Material properties and function can be altered either by in situ enzyme immobilization or post-synthetic acid elution of encapsulated additives.
07:14
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
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Cited by 4 •
2022
Novel nanocomposites of graphene nanoribbons and hydroxyapatite nanoparticles were prepared using solution-phase synthesis. These hybrids when employed in bioactive scaffolds can exhibit potential applications in tissue engineering and bone regeneration.
FAQs
Organic templates and functionalized surfaces provide locations where calcium and phosphate ions can nucleate and grow. Proteins or polymers may further regulate crystal size and organization during formation. This control helps reproduce structural features of apatite in bone and teeth rather than producing mineral without an organizing environment. In bioengineering, template-mediated growth supports the design of more tissue-like materials.
Aqueous, physiological-like conditions provide the setting in which calcium and phosphate ions nucleate and grow, making the formation process resemble mineral production associated with biological tissues. Their use is important because the resulting material is engineered under conditions linked to bone and tooth apatite. This biomimetic route can enhance chemical similarity and biological compatibility for bioengineering applications.
Proteins and polymers can regulate the size and organization of hydroxyapatite crystals as they form. This role is distinct from simply supplying calcium or phosphate, because these organic components influence how the mineral develops on a template or functionalized surface. Controlling crystal organization helps researchers tailor the resulting material for biomimetic designs and regenerative bioengineering systems.
A basic workflow combines calcium and phosphate ions with an organic template or a functionalized surface in an aqueous, physiological-like environment. Proteins or polymers may be included to regulate crystal size and organization. Under these conditions, the ions nucleate and grow into mineral, producing a material whose composition and structure can be engineered toward those of biological apatite.
Bioinspired hydroxyapatite can be incorporated into bone substitutes, implant coatings, scaffolds, and controlled delivery systems. Its engineered chemical similarity to biological apatite and its biological compatibility make it useful across these different formats. The material may therefore serve either as a mineral component within a regenerative construct or as a surface or carrier element in a bioengineering design.
Studying bioinspired hydroxyapatite provides a way to examine how mineralized tissues form under controlled, biomimetic conditions. Reproducing aspects of apatite composition, structure, and formation can clarify the relationship between mineral growth and organic regulation. In bioengineering, that knowledge supports the development of regenerative biomaterials designed to interact more appropriately with mineralized tissues.