Osteoarthritis Hand
Osteoarthritis Hand - Related Videos
07:58
Establishment of a Surgically-induced Model in Mice to Investigate the Protective Role of Progranulin in Osteoarthritis
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Cited by 47 •
2014
We describe a protocol for the destabilization of the medial meniscus (DMM) model in mice, an effective tool for osteoarthritis (OA) research. In addition, we have demonstrated that deficiency of progranulincan exaggerate OA development and progression by using this model, indicating that progranulin plays a protective role in the pathogenesis of OA.
09:26
The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
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Cited by 181 •
2016
Osteoarthritis (OA), or degenerative joint disease, is a debilitating condition associated with pain that remains only partially controlled by available analgesics. Animal models are being developed to improve our understanding of OA-related pain mechanisms. Here we describe the methodology for the monoiodoacetate model of OA pain in the mouse.
08:09
The Rubber Hand Illusion
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2023
Source: Laboratory of Jonathan Flombaum—Johns Hopkins University Reaching for objects, walking without hitting obstacles, landing on a chair as you sit (instead of falling to the floor), these and all our physical actions depend on an ability to perceive our own bodies in space, to know where our limbs are relative to one another and relative to the rest of the world. One way that the human brain encodes this information is called proprioception, the brain relies on its own control and feedback...
09:35
Measurement of the Hand Transmitted Vibration of the Human Hand Arm System During Operation of a Hand Tractor
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Cited by 1 •
2021
Here, we present a standardized method for measurement of the hand transmitted vibration from handles of a single-axle tractor with special reference to changes in grip force and vibration frequency.
01:23
Hand hygiene
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2023
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms. Hand washing...
FAQs
Progressive cartilage breakdown changes how forces move through affected finger and thumb joints. As cartilage becomes less effective, load distribution shifts toward surrounding structures, while subchondral bone remodels. Osteophytes, or bony overgrowths, may develop, and episodic synovial inflammation can add swelling and stiffness. Together, these changes can reduce grip and pinch performance, linking structural progression with functional limitations.
Symptoms may fluctuate when episodic synovial inflammation accompanies the underlying structural changes. This inflammation can produce periods of swelling and stiffness, even though the broader condition also involves progressive cartilage breakdown and bone remodeling. Pain and stiffness may therefore affect hand use differently across episodes, while reduced grip or pinch strength reflects the functional impact.
Distinguishing hand osteoarthritis from inflammatory arthritis requires more than symptoms alone. Clinicians combine the patient’s symptom history with physical examination and, when indicated, radiographs. This combined assessment helps identify whether the presentation fits degenerative joint disease or suggests inflammatory arthritis, supporting a more appropriate care plan.
Assessment begins with symptom history and a physical examination of the hand, including the affected finger or thumb joints and their functional effects. Radiographs may be added when indicated. These sources of information help clinicians evaluate pain, stiffness, swelling, and impaired hand use, distinguish osteoarthritis from inflammatory arthritis, and guide treatment decisions.
Initial care focuses on preserving function rather than addressing symptoms alone. Education helps patients understand the condition, while therapeutic exercise supports hand use. Activity modification can reduce aggravating demands, and splinting may provide additional support. Symptom-relief strategies can be incorporated as needed, with the overall approach aimed at maintaining grip, pinch, and daily hand function.
Injections or surgery are considered for selected cases rather than as routine first steps. The decision follows clinical assessment and the individual’s symptoms, functional limitations, and response to approaches such as education, exercise, activity modification, splinting, and symptom relief. These options may be discussed when preserving hand function requires additional intervention.