Myocardial Strain Analysis

Myocardial strain analysis is an imaging-based method for quantifying how much heart muscle deforms during contraction and relaxation, providing sensitive information about myocardial function beyond ejection fraction alone. Using echocardiography, particularly speckle-tracking, the technique follows natural acoustic patterns through successive frames to calculate deformation along longitudinal, radial, and circumferential axes; strain is typically expressed as a percentage change in length. In medicine, these measurements help identify regional or subclinical dysfunction in ischemia, cardiomyopathies, and other cardiac disorders, while supporting treatment monitoring and risk assessment.

Myocardial Strain Analysis - Related Videos

Research

JoVE Journal - Medicine
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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

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Cited by 186 •

2011

An accurate and practical method to measure parameters like strain in myocardial tissue is of great clinical value, since it has been shown, that strain is a more sensitive and earlier marker for contractile dysfunction than the frequently used parameter EF.

Research

JoVE Journal - Medicine
Free Sample

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

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Cited by 9 •

2010

High frequency Doppler ultrasound is a novel technology for assessing regional myocardial function. This work presents first evidence demonstrating applicability of this versatile imaging platform for the repeated measure of myocardial strain, dp/dt, and mitral regurgitation in the ischemia-reperfused (IR) murine heart.

Education

JoVE Core - Mechanical Engineering

Three-Dimensional Analysis of Strain

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2024

Three-dimensional strain analysis is crucial for understanding how materials deform under stress, particularly in elastic, homogeneous materials. This method employs principal stress axes to simplify complex stress states into more understandable forms. Subjected to stress, a small cubic element within a material either expands or contracts along these axes, transforming into a rectangular parallelepiped. This transformation effectively illustrates the material's deformation. The principal...

Bending of Curved Members - Strain Analysis

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2024

The mechanics of deformation in curved members, such as beams or arches, under bending moments, involve complex responses. When such a member, symmetric about the y-axis and shaped like a segment of a circle centered at point C, is subjected to equal and opposite forces, its curvature and surface lengths change significantly. This alteration results in the shift of the curvature's center from C to C', indicating a tighter curve. The important part of bending analysis for such a member is the...

A Microscopic 2,3,5-Triphenyltetrazolium Chloride Assay for Accurate and Reliable Analysis of Myocardial Injury

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2025

The present 2,3,5-Triphenyltetrazolium Chloride (TTC) assay introduces a refined TTC staining protocol that enables the analysis of myocardial injury at microscopic resolution, producing high-quality images that allow for accurate and reliable assessment of infarct size and cardiomyocyte viability at the cellular level.

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