Rodent Endoscopy
Rodent Endoscopy - Related Videos
07:54
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
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Cited by 16 •
2016
The aim of this study was to establish a standardized protocol for sleep endoscopy to differentiate obstruction patterns in obstructive sleep apnea (OSA). Target-controlled infusion (TCI) of the sedative was combined with real-time monitoring of the depth of sedation using bispectral analysis.
14:12
Rodent Identification II
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2015
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Animal records must be accurately maintained to ensure that data collection is correct. Records range from maintaining information on cage cards to having a detailed database with all of the relevant information on each animal. The primary component of recordkeeping is the individual identification of research animals. There are a variety of methods suitable for identifying mice and rats. This...
12:13
Considerations for Rodent Surgery
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2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...
01:34
Environmental Enrichment for Rodents
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2026
All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Environmental enrichment involves objects and practices that encourage natural behaviors, improve psychological well-being, and promote better welfare in laboratory rodents. Environmental enrichment should be tailored to the...
05:16
Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
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Cited by 2 •
2022
Laparoscopy-endoscopy cooperative surgery is appropriate for the treatment of gastric gastrointestinal stromal tumors less than 5 cm in size. It can achieve the respective advantages of endoscopic and laparoscopic surgeries while avoiding their drawbacks.
FAQs
The illuminated optical system directs light within the animal, while the camera receives and transmits a magnified view for observation. Depending on the setup, access occurs through a natural passage or a small surgical opening. This arrangement supports direct visualization while reducing the need to euthanize the animal for every observation.
Magnification makes internal structures easier to observe and document during each examination. This matters in longitudinal experiments, where researchers compare observations from the same living mouse or rat over time rather than relying only on separate animals or a single terminal observation. Consistent visual records can therefore strengthen assessment of changing conditions.
A repeated-use design enables serial observation in the same subject, improving experimental efficiency and reducing the need for euthanasia. In neuroscience, serial views can be related to disease progression, treatment assessment, and behavioral or functional measurements. The value lies in tracking relationships among anatomical and associated physiological changes across time.
A typical examination uses a rigid or flexible endoscope, introduces it through a natural passage or small surgical opening, and illuminates the target area. The camera then transmits magnified images for direct inspection. Where the system permits, researchers may also collect tissue or perform an intervention before repeating the process for longitudinal comparison.
In neuroscience, researchers may use the technique to examine neural or associated physiological changes over time and to evaluate disease models or treatments. Because observations can be repeated, investigators can relate visible findings to behavioral or functional measurements collected during the study. This connects anatomical evidence with broader experimental outcomes in mice and rats.
The method can provide direct visual observations, longitudinal records, and, in some systems, tissue samples or interventions. These outputs support evaluation of disease models and treatments while improving experimental efficiency and animal-based research outcomes. Its broader contribution is combining within-animal observation with physiological, behavioral, or functional measurements rather than treating each finding as isolated.