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July 21, 2022
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Summary
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זיהום בנגיף שפעת A (IAV) מפעיל את הקספאזות שמבקעות חלבונים פונדקאיים ונוגפיים, אשר בתורם הם בעלי תפקידים פרו-ויראליים. על ידי שימוש במעכבים, הפרעות RNA, מוטגנזה מכוונת אתר, וטכניקות כתם מערביות ו- RT-qPCR, זוהו קספאזות בתאי יונקים נגועים המבקעים קורטקטין מארח והיסטון דאקטילאזות.
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Cite this Article
Husain, M. Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection. J. Vis. Exp. (185), e64189, doi:10.3791/64189 (2022).
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