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JoVE Core

Cell Biology

Video textbook for undergraduate courses: Visualized concepts and experiments

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43 Chapters

550+ Videos

4,050+ Multiple Choice Questions

Table of Contents

Chapter 1

Cells, Genomes, and Evolution

15 Videos

26 Minutes

What are Cells?

What are Cells?

32.9K views

The Tree of Life – Bacteria, Archaea, and Eukaryotes

The Tree of Life – Bacteria, Archaea, and Eukaryotes

14.7K views

Prokaryotic Cells

Prokaryotic Cells

36.2K views

Eukaryotic Compartmentalization

Eukaryotic Compartmentalization

11.8K views

Eukaryotic Evolution

Eukaryotic Evolution

35.5K views

Animal and Plant Cell Structure

Animal and Plant Cell Structure

30.6K views

Cytoplasm

Cytoplasm

5.9K views

The Nucleus

The Nucleus

4.8K views

The DNA Helix

The DNA Helix

21.1K views

The Central Dogma

The Central Dogma

23.4K views

Mutations

Mutations

39.4K views

Genome Size and the Evolution of New Genes

Genome Size and the Evolution of New Genes

2.5K views

Gene Families

Gene Families

2.6K views

Gene Evolution – Fast or Slow?

Gene Evolution – Fast or Slow?

2.9K views

Types of Genetic Transfer Between Organisms

Types of Genetic Transfer Between Organisms

5.4K views

Chapter 2

Biochemistry of the Cell

12 Videos

29 Minutes

The Periodic Table and Organismal Elements

The Periodic Table and Organismal Elements

18.8K views

Functional Groups

Functional Groups

21.8K views

Types of Chemical Bonds

Types of Chemical Bonds

21.1K views

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

18K views

Polymers

Polymers

21.1K views

What are Lipids?

What are Lipids?

7.7K views

Structure of Lipids

Structure of Lipids

10.9K views

Chemistry of Carbohydrates

Chemistry of Carbohydrates

8.8K views

Nucleic Acids

Nucleic Acids

7.7K views

Protein and Protein Structures

Protein and Protein Structures

10.7K views

pH Regulation in Cells

pH Regulation in Cells

6.3K views

Chemistry of the Cell

Chemistry of the Cell

7K views

Chapter 3

Energy and Catalysis

22 Videos

30 Minutes

The First Law of Thermodynamics

The First Law of Thermodynamics

6.1K views

The Second Law of Thermodynamics

The Second Law of Thermodynamics

5.5K views

Enthalpy within the Cell

Enthalpy within the Cell

6.1K views

Entropy within the Cell

Entropy within the Cell

11K views

An Introduction to Free Energy

An Introduction to Free Energy

8.7K views

Endergonic and Exergonic Reactions in the Cell

Endergonic and Exergonic Reactions in the Cell

15.5K views

The Equilibrium Binding Constant and Binding Strength

The Equilibrium Binding Constant and Binding Strength

9.2K views

Free Energy and Equilibrium

Free Energy and Equilibrium

6.5K views

Non-equilibrium in the Cell

Non-equilibrium in the Cell

4.7K views

Oxidation and Reduction of Organic Molecules

Oxidation and Reduction of Organic Molecules

7.1K views

Introduction to Enzymes

Introduction to Enzymes

19.1K views

Enzymes and Activation Energy

Enzymes and Activation Energy

12.2K views

Introduction to Enzyme Kinetics

Introduction to Enzyme Kinetics

26.9K views

Turnover Number and Catalytic Efficiency

Turnover Number and Catalytic Efficiency

10.4K views

Catalytically Perfect Enzymes

Catalytically Perfect Enzymes

4.1K views

Introduction to Mechanisms of Enzyme Catalysis

Introduction to Mechanisms of Enzyme Catalysis

8.4K views

Ligand Binding and Linkage

Ligand Binding and Linkage

3.2K views

Cooperative Allosteric Transitions

Cooperative Allosteric Transitions

2.6K views

Ribozymes

Ribozymes

2.7K views

ATP Energy Storage and Release

ATP Energy Storage and Release

10.7K views

ATP and Macromolecule Synthesis

ATP and Macromolecule Synthesis

5.8K views

Coupled Reactions

Coupled Reactions

8K views

Chapter 4

Introduction to Metabolism

12 Videos

16 Minutes

Overview of Metabolism

Overview of Metabolism

31.7K views

Carbohydrate Metabolism

Carbohydrate Metabolism

11.4K views

Glycolysis: Preparatory Phase

Glycolysis: Preparatory Phase

13.9K views

Glycolysis: Pay-off Phase

Glycolysis: Pay-off Phase

10.2K views

Fates of Pyruvate

Fates of Pyruvate

8.8K views

Role of Reduced Coenzymes NADH and FADH₂

Role of Reduced Coenzymes NADH and FADH₂

12.2K views

Overview of Nitrogen Metabolism

Overview of Nitrogen Metabolism

8.4K views

Overview of Fatty Acid Metabolism

Overview of Fatty Acid Metabolism

31.2K views

Sugars as Energy Storage Molecules

Sugars as Energy Storage Molecules

8.7K views

Fats as Energy Storage Molecules

Fats as Energy Storage Molecules

25.6K views

Regulation of Metabolism

Regulation of Metabolism

9.8K views

Positive and Negative Feedback Loops

Positive and Negative Feedback Loops

19.8K views

Chapter 5

Protein Structure

10 Videos

22 Minutes

What are Proteins?

What are Proteins?

15.1K views

Protein Organization

Protein Organization

6.8K views

Protein Folding

Protein Folding

8.3K views

Protein Families

Protein Families

3.4K views

Conservation of Protein Domains

Conservation of Protein Domains

3.2K views

Globular and Fibrous Proteins

Globular and Fibrous Proteins

4.2K views

Intrinsically Disordered Proteins

Intrinsically Disordered Proteins

2.4K views

Protein Complex Assembly

Protein Complex Assembly

2.1K views

Conjugated Proteins

Conjugated Proteins

2.7K views

Amyloid Fibrils

Amyloid Fibrils

5.5K views

Chapter 6

Protein Function

12 Videos

25 Minutes

Ligand Binding Sites

Ligand Binding Sites

7.8K views

Protein-Protein Interfaces

Protein-Protein Interfaces

3.8K views

Conserved Binding Sites

Conserved Binding Sites

1.7K views

Cofactors and Coenzymes

Cofactors and Coenzymes

11.2K views

Cooperative Allosteric Transitions

Cooperative Allosteric Transitions

2.3K views

Protein Kinases and Phosphatases

Protein Kinases and Phosphatases

3.9K views

GTPases and their Regulation

GTPases and their Regulation

2.3K views

Covalently Linked Protein Regulators

Covalently Linked Protein Regulators

1.7K views

Protein Complexes with Interchangeable Parts

Protein Complexes with Interchangeable Parts

1.9K views

Mechanical Protein Function

Mechanical Protein Function

2.1K views

Structural Protein Function

Structural Protein Function

2.8K views

Protein Networks

Protein Networks

2.4K views

Chapter 7

Structure and Organization of DNA

10 Videos

21 Minutes

DNA as a Genetic Template

DNA as a Genetic Template

6.9K views

Structure of a Gene

Structure of a Gene

12.8K views

Chromosome Structure

Chromosome Structure

4.9K views

The Nucleosome

The Nucleosome

3.6K views

Chromatin Packaging

Chromatin Packaging

8.4K views

Euchromatin

Euchromatin

2.9K views

Heterochromatin

Heterochromatin

3.7K views

Histone Modification

Histone Modification

3.5K views

Lampbrush Chromosomes

Lampbrush Chromosomes

2.5K views

Polytene Chromosomes

Polytene Chromosomes

3.1K views

Chapter 8

DNA Replication and Repair

17 Videos

34 Minutes

Base-pairing and DNA Repair

Base-pairing and DNA Repair

64.9K views

The DNA Replication Fork

The DNA Replication Fork

15.7K views

Lagging Strand Synthesis

Lagging Strand Synthesis

13.8K views

The Replisome

The Replisome

6.9K views

Proofreading

Proofreading

6.5K views

Replication in Prokaryotes

Replication in Prokaryotes

25.2K views

Replication in Eukaryotes

Replication in Eukaryotes

14.2K views

Telomeres and Telomerase

Telomeres and Telomerase

5.3K views

Overview of DNA Repair

Overview of DNA Repair

7.7K views

Base Excision Repair

Base Excision Repair

3.9K views

Nucleotide Excision Repair

Nucleotide Excision Repair

3.7K views

Mismatch Repair

Mismatch Repair

5.1K views

Fixing Double-strand Breaks

Fixing Double-strand Breaks

3.3K views

Homologous Recombination

Homologous Recombination

4.8K views

Gene Conversion

Gene Conversion

2.4K views

DNA Damage Can Stall the Cell Cycle

DNA Damage Can Stall the Cell Cycle

2.7K views

Restarting Stalled Replication Forks

Restarting Stalled Replication Forks

2K views

Chapter 9

Transcription: DNA to RNA

18 Videos

35 Minutes

What is Gene Expression?

What is Gene Expression?

8.9K views

RNA Structure

RNA Structure

5K views

Types of RNA

Types of RNA

6.1K views

Transcription

Transcription

23.8K views

Bacterial RNA Polymerase

Bacterial RNA Polymerase

8.8K views

Eukaryotic RNA Polymerases

Eukaryotic RNA Polymerases

6.8K views

General Transcription Factors

General Transcription Factors

5.5K views

RNA Polymerase II Accessory Proteins

RNA Polymerase II Accessory Proteins

3.2K views

Transcription Elongation Factors

Transcription Elongation Factors

3.8K views

Pre-mRNA Processing: Modification of pre-mRNA Ends

Pre-mRNA Processing: Modification of pre-mRNA Ends

9.7K views

Pre-mRNA Processing: RNA Splicing

Pre-mRNA Processing: RNA Splicing

5.4K views

Chromatin Structure and RNA Splicing

Chromatin Structure and RNA Splicing

2.8K views

Alternative RNA Splicing

Alternative RNA Splicing

3.9K views

Nuclear Export of mRNA

Nuclear Export of mRNA

4.6K views

Transfer RNA Synthesis

Transfer RNA Synthesis

2.9K views

Ribosomal RNA Synthesis

Ribosomal RNA Synthesis

3.3K views

The Nucleolus

The Nucleolus

4.1K views

Additional Subnuclear Structures

Additional Subnuclear Structures

2.2K views

Chapter 10

Translation: RNA to Protein

11 Videos

24 Minutes

Translation

Translation

15.2K views

Ribosomes

Ribosomes

7.9K views

tRNA Activation

tRNA Activation

6.9K views

Initiation of Translation

Initiation of Translation

6.6K views

Termination of Translation

Termination of Translation

5.6K views

Improving Translational Accuracy

Improving Translational Accuracy

2.7K views

Nonsense-mediated mRNA Decay

Nonsense-mediated mRNA Decay

2.9K views

Molecular Chaperones and Protein Folding

Molecular Chaperones and Protein Folding

13.2K views

The Proteasome

The Proteasome

3.5K views

Regulated Protein Degradation

Regulated Protein Degradation

2.6K views

Proteins: From Genes to Degradation

Proteins: From Genes to Degradation

3.6K views

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