Liver Parenchyma Transection

Liver parenchyma transection is the controlled division of liver tissue during hepatic surgery, enabling surgeons to remove diseased or injured segments while preserving functioning liver. During transection, the parenchyma is separated along a planned resection plane, with systematic identification and sealing of intrahepatic blood vessels and bile ducts to limit bleeding and bile leakage. This technique is central to hepatectomy for tumors, transplantation, and selected traumatic injuries; understanding liver anatomy, tissue planes, and hemostatic principles supports safer operations, effective cancer treatment, and preservation of postoperative liver function.

Liver Parenchyma Transection - Related Videos

Research

JoVE Journal - Biology

Right Hemihepatectomy by Suprahilar Intrahepatic Transection of the Right Hemipedicle using a Vascular Stapler

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Cited by 1 •

2010

This video describes a right hemihepatectomy with intrahepatic transection of the right hemipedicle leaving the hepatoduodenal ligament completely untouched.

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

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2025

Here, we present a protocol to establish a long-term liver cold storage and transplantation model in Daurian ground squirrel (DGS), which has been technically challenging in standard rodent models.

Research

JoVE Journal - Medicine
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Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

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2025

This protocol involves a laparoscopic anatomical resection of liver segment VII with liver parenchymal transection following a priority approach. This technique is unaffected by anatomical variations.

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

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Cited by 6 •

2017

Inducing rapid liver hypertrophy using Associating Liver Partition and Portal vein ligation for a Staged hepatectomy (ALPPS) has been proposed for resection of borderline resectable liver tumors. This model may elucidate mechanisms involved in rapid hypertrophy and allows testing of drugs that promote or block the acceleration of regeneration.

Research

JoVE Journal - Biology
Free Sample

Isolation of Rat Portal Fibroblasts by In situ Liver Perfusion

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Cited by 22 •

2012

A technique for isolating portal fibroblasts from rat liver is described. Livers are perfused and digested in situ with collagenase, followed by ex vivo digestion of the liver slurry and size selection of cells. This method provides a pure population of portal fibroblasts without the need for passage in culture.

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