Susceptibility Weighted Imaging
Susceptibility Weighted Imaging - Related Videos
01:09
Quantitative Susceptibility Mapping of a Human Brain Using Ex-Vivo Magnetic Resonance Imaging
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2025
Quantitative susceptibility mapping, or QSM, quantifies the magnetic susceptibility of brain tissue, which reflects its cellular composition, like myelin content.Begin by acquiring ex-vivo magnetic resonance imaging or MRI data of a fixed human brain hemisphere.Use 3D gradient magnetic fields to magnetize the tissue and collect signals at multiple time points or echoes to reduce background noise and artifacts and enhance the signals.Generate phase maps for all echoes, ensuring the removal of...
17:06
Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
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Cited by 17 •
2012
We describe a novel approach for simultaneous analysis of brain function and structure using magnetic resonance imaging (MRI). We assess brain structure with high-resolution diffusion-weighted imaging and white-matter fiber tractography. Unlike standard structural MRI, these techniques allow us to directly relate anatomical connectivity to functional properties of brain networks.
04:09
Diffusion-Weighted Imaging of the Rat Hippocampus with Mild Traumatic Brain Injury
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2025
Source: Braeckman, K., et. al. Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury. J. Vis. Exp. (2019)This video demonstrates the use of diffusion-weighted imaging to assess microstructural changes in a rat hippocampus following mild traumatic brain injury (mTBI), highlighting axonal injury through precise MRI scanning and diffusion analysis.
08:27
Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
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2025
Here, we present a protocol to establish a closed-head injury animal model replicating the neuroimage outcome of uncomplicated mild traumatic brain injury with the preserved brain structure in the acute phase and long-term brain atrophy. Longitudinal magnetic resonance imaging is the primary method used for evidence.
00:57
Weighted Mean
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2023
While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others. For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
FAQs
SWI improves visibility by analyzing two complementary signal features from a gradient-echo acquisition. Magnitude data describe signal strength, while phase data capture susceptibility-related shifts that may be subtle on ordinary structural images. Combining them increases contrast around veins and abnormal deposits, allowing these structures to stand out rather than being assessed from anatomy alone.
Paramagnetic substances such as deoxyhemoglobin, hemosiderin, and iron disturb the local magnetic environment. That disturbance creates susceptibility differences and associated phase shifts in the MR signal. Because SWI uses phase information alongside magnitude data, these substances can generate conspicuous findings even when their related vascular or tissue changes are subtle on conventional structural scans.
Compared with conventional structural MRI, SWI emphasizes magnetic susceptibility rather than anatomy alone. This makes it particularly useful for detecting or depicting veins, microbleeds, hemorrhage, calcification, and iron accumulation. The added sensitivity does not replace structural imaging; instead, it contributes complementary information about vascular, mineral, and blood-product changes in brain tissue.
An SWI examination depends on a gradient-echo acquisition that preserves both magnitude and phase information. The magnitude component supplies signal-intensity data, whereas the phase component records susceptibility-related shifts. Using these paired data is essential because the contrast of interest arises from local magnetic differences, not from structural anatomy alone.
SWI supports neuroscience investigations across several disease contexts. Researchers can apply it to stroke, traumatic brain injury, vascular disorders, and neurodegenerative disease, where subtle venous, hemorrhagic, mineral, or iron-related changes may matter. Its ability to strengthen visualization of these changes helps connect MRI findings with brain pathology and disease-related structural alterations.
At the level of experimental outcomes, SWI can provide information about cerebral venous anatomy and identify findings associated with microbleeds, hemorrhage, calcification, or iron accumulation. These observations help characterize subtle vascular and tissue changes, making the technique useful when a study needs more than conventional structural anatomy to evaluate brain pathology.