Immune Suppression
Immune Suppression - Related Videos
14:01
Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
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2011
Tregs are potent suppressors of the immune system. There is a lack of unique surface markers to define them, hence, definitions of Tregs are primarily functional. Here we describe an optimized in vitro assay capable of identifying immune imbalance in subjects at risk to develop T1D.
09:38
Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
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Cited by 7 •
2016
This protocol describes how to determine whether pharmacological treatments for experimental autoimmune encephalomyelitis show CNS protection as a consequence of suppressing immune cell infiltration or are neuroprotective during the onslaught of immune cell infiltration.
08:34
The Measurement and Treatment of Suppression in Amblyopia
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Cited by 54 •
2012
Amblyopia is a developmental disorder of the visual cortex that is often accompanied by strong suppression of one eye. We present a new technique for measuring and treating interocular suppression in patients with amblyopia that can be deployed using virtual reality goggles or a portable iPod Touch device.
04:29
Visualizing Transcriptional Suppression in Virus-Infected Cells
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2026
Source: Kalveram, B. et al. Using Click Chemistry to Measure the Effect of Viral Infection on Host-Cell RNA Synthesis. J. Vis. Exp. (2013)This video demonstrates the use of click chemistry and fluorescence microscopy to visualize nascent RNA transcription in mammalian cells. It highlights how viral infection suppresses host transcription by comparing fluorescent signals between infected and control cells.
01:38
What is the Immune System?
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2019
Overview The immune system comprises diverse biological structures and processes that protect the body from disease. These processes can be classified into innate and adaptive immunity. To work effectively, the immune system needs to detect pathogens by distinguishing the body’s own structures from foreign elements. If this determination fails, autoimmune diseases occur in which the immune system reacts against the body’s own tissue. The Innate Immune System Acts Fast and Non-specifically
FAQs
Prolonged psychological stress can engage signaling among the brain, sympathetic nervous system, and hypothalamic-pituitary-adrenal axis. These pathways change hormone and neurotransmitter levels, which may modify communication among immune cells and alter inflammatory responses. This framework allows psychoneuroimmunology researchers to connect sustained psychological experiences with immune-related outcomes while recognizing that stress is one contributing influence.
Hormones and neurotransmitters serve as signaling intermediaries between psychological stress and immune processes. Changes in their levels may affect how immune cells communicate and how inflammatory responses are regulated. Studying these intermediaries helps researchers move beyond a simple mind-body association by examining a plausible biological pathway linking stress-related signaling with altered immune activity.
Trauma, mood disorders, and coping processes represent psychological contexts that researchers can examine alongside chronic stress and immune-related outcomes. Their inclusion helps distinguish whether different mental health experiences show different relationships with infection risk, inflammation, or recovery. This broadens investigation beyond a single stress pathway and supports a more detailed psychology-focused analysis of immune function.
Such studies may examine relationships among psychological conditions or stress, infection risk, inflammatory responses, and recovery. The goal is not limited to measuring immune activity alone; researchers can also consider mental health and broader health outcomes. This helps place immune findings within a larger account of how psychological and physiological processes interact.
Behavioral interventions provide a way to investigate whether addressing psychological processes is associated with changes in immune-related or health outcomes. Within psychoneuroimmunology, they can connect coping and mental health with immune function, inflammation, infection risk, or recovery. Their relevance lies in testing the health implications of psychological processes rather than isolating biology from experience.
Clinical research may connect mental health with immune function when investigating how psychological conditions, stress-related processes, and health outcomes occur together. Such work can examine infection risk, inflammation, recovery, and overall health within the same research perspective. The connection is especially relevant to psychoneuroimmunology because it links psychological assessment with biological and clinical questions.