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Journal / Bioengineering / A-Microfluidic gebaseerd Elektrochemische Biochip …
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Bioengineering

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A-Microfluidic gebaseerd Elektrochemische Biochip voor-Label vrij DNA hybridisatie-analyse

Article DOI: 10.3791/51797-v • 14:53 min • September 10th, 2014
September 10th, 2014 •
1, 1, 2, 2, 1
1MEMS Sensors and Actuators Laboratory (MSAL), Department of Electrical and Computer Engineering, Institute for Systems Research, University of Maryland, 2Institute for Bioscience and Biotechnology Research, Fischell Department of Bioengineering, University of Maryland

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We presenteren een microfluidic gebaseerde elektrochemische biochip voor DNA hybridisatie detectie. Na ssDNA probe functionalisering, de specificiteit, gevoeligheid en detectielimiet bestudeerd met complementaire en niet complementaire ssDNA targets. De resultaten tonen de invloed van de DNA hybridisatie aan het elektrochemische systeem, met een detectielimiet van 3,8 nM.

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Biotechniek elektrochemische impedantie spectroscopie DNA hybridisatie biosensor biochip microfluidics label-free detectie beperkte verspreiding microfabrication
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