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Etablering af en human myelomatose xenograftmodel i kylling til Studieinformationen tumorvækst, invasion og angiogenese

Article DOI: 10.3791/52665-v • 10:04 min • May 1st, 2015
May 1st, 2015 •
*1,4, *1,2, 1, 1,3
1Department of Internal Medicine V, Innsbruck Medical University, 2Oncotyrol GmbH, 3Tyrolean Cancer Research Institute, 4Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute
* These authors contributed equally

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Humane multipelt myelom (MM) celler kræver støttende mikromiljø mesenchymale celler og ekstracellulære matrixkomponenter for overlevelse og proliferation. Vi etablerede en in vivo kylling embryo model med indpodede humane myelom og mesenkymceller at studere virkningerne af kræft lægemidler på tumorvækst, invasion og angiogenese.

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Medicin CAM angiogenese mesenkymale celler multipelt myelom GFP 3- dimensionelle vævskultur xenotransplantater tumor
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