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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

DOI:
10.3791/54052-v

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09:25 min

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May 31, 2016

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, ,
1Laboratory of Endocrinology and Receptor Biology,National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 2Murine Phenotyping Core,National Heart, Lung, and Blood Institute, National Institutes of Health

Capitoli

  • 00:05Titolo
  • 00:48Treadmill Set Up
  • 01:43Treadmill Training
  • 05:04Treadmill Fatigue Test
  • 07:11Results: Fatigue Testing with 5-FU Treatment
  • 08:51Conclusion

Summary

Traduzione automatica

Traduzione automatica

Fatigue is a common, undertreated and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding and future treatment of fatigue. To that end, the current protocol provides a novel means of measuring fatigue-like behavior in the mouse.

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TreadmillFatigueComportamentoMouseAssayInterventionAnti-fatigueTrainingTestingShock GridSpeedWalkingExploring

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