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Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
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Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System

Article DOI: 10.3791/55672-v • 10:44 min • May 24th, 2017
May 24th, 2017 •
1, 1, 1, 2, 1, 1,3, 1
1Jobst Vascular Research Laboratory, University of Michigan Medical School, 2Department of Engineering, Purdue University, 3Department of Surgery, Section of Vascular Surgery, University of Michigan Health System

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This protocol describes a method for exposing rodents to electronic cigarette vapor (E-vapor) and cigarette smoke. Exposure chambers are constructed by modifying anesthesia chambers with an automated pumping system that delivers E-vapor or cigarette smoke to rodents. This system can easily be modified to accommodate many experimental endpoints.

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Electronic Cigarette Vapor Cigarette Smoke In Vivo Exposure System Health Effects Pulmonary Diseases Cardiovascular Diseases Nicotine Lung Cancer COPD Allergies Asthma Tobacco Smoke Chamber Disease Models Abdominal Aortic Aneurysm Biochemical Changes E-vapor Safety Silicone Tubing
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