In Vitro e In Vivo rilevamento di Mitophagy in cellule umane, C. Eleganse topi

17.5K visualizzazioni

Citato da 33

08:40 min.

22 novembre 2017

10.3791/56301-v

22 novembre 2017

17.5K visualizzazioni

Evandro F. Fang¹^,⁶ , Konstantinos Palikaras² , Nuo Sun³ , Elayne M. Fivenson¹ , Ryan D. Spangler⁴ , Jesse S. Kerr¹ , Stephanie A. Cordonnier¹ , Yujun Hou¹ , Eszter Dombi⁵ , Henok Kassahun⁶ , Nektarios Tavernarakis²^,⁷ , Joanna Poulton⁵ , Hilde Nilsen⁶ , Vilhelm A. Bohr¹^,⁸

¹Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, ²Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, ³Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, ⁴Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, ⁵Nuffield Department of Obstetrics and Gynaecology, University of Oxford, ⁶Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, ⁷Department of Basic Sciences, Faculty of Medicine, University of Crete, ⁸Danish Center for Healthy Aging, University of Copenhagen

Mitophagy, il processo di schiarimento danneggiato i mitocondri, è necessario per la manutenzione di salute e omeostasi mitocondriale. Questo articolo presenta alcune delle mitophagy più recenti metodi di rilevazione in Caenorhabditis eleganse cellule umane in topi.