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Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm
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Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm

Article DOI: 10.3791/56983-v • 08:29 min • June 7th, 2018
June 7th, 2018 •
1, 1, 1, 1
1Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología, Universitat de València

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This protocol describes the Conditioned Place Preference (CPP) as a model of relapse. This procedure permits the measurement of relapse in laboratory animals, considering the impact of drug-associated environmental cues as craving and relapse in abstaining addicts is currently the focus of drug-abuse treatment programs.

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Reinstatement Drug-seeking Conditioned Place Preference Paradigm Laboratory Animals Drug Addiction Environmental Cues Stress Approach Behavior Incentive Motivational Value Context Stimuli Relapse Environmental Manipulation Ethology Triggers Human Relapse Environmental Change Room Condition Environment Condition Mates Of The Opposite Sex Noises Light Conditions Drug Response Stress-induced Reinstatement Social Defeat
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