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Detection of Endotoxin in Nano-formulations Using Limulus Amoebocyte Lysate (LAL) Assays
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Capitoli
- 00:04Titolo
- 00:32Turbidity Limulus Amoebocyte Lysate (LAL) Assay
- 02:26Sample Loading and Preparation and Gel-Clot LAL
- 04:27Results: Representative Detection of Endotoxin in PEGylated Liposomal Doxorubicin Using LAL Assays
- 05:12Conclusion
Detection of endotoxins in engineered nanomaterials represents one of the grand challenges in the field of nanomedicine. Here, we present a case study that describes the framework composed of three different LAL formats to estimate potential endotoxin contamination in nanoparticles.
Tags
EndotoxinNano-formulationsLimulus Amoebocyte Lysate (LAL) AssaysCalibration StandardControl Standard EndotoxinLAL Grade WaterQuality ControlInstrument SettingsTest IDData GroupHardwareLAL MethodSerial NumberSystem IDSerial PortSample IDNegative ControlStandard CurveTest SamplesInhibition Enhancement ControlDilution
