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Behavioral And Physiological Analysis In A Zebrafish Model Of Epilepsy

Article DOI: 10.3791/58837-v • 08:26 min • October 19th, 2021
October 19th, 2021 •
*1,2, *3, 3, 1,2, 1,2
1University Paris Descartes Hospital Necker-Enfants Malades, Institut Imagine, 2Institut du Cerveau et de la Moelle épinière - ICM, Sorbonne Universités Paris, 3Transylvanian Institute of Neuroscience (TINS)
* These authors contributed equally

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Here, we present a protocol for the development and the characterization of a zebrafish model of epilepsy resulting from the transient inhibition of the DEPDC5 gene.

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Behavioral Analysis Physiological Analysis Zebrafish Model Epilepsy WC5 Gene Knockdown Phenotype Evaluation Micro Injection Zebrafish Mating Tanks Embryo Water Petri Dishes Glass Needle Injection Solution Micro Injector Air Compressor Nanoliter Injection Volume Dissecting Binocular Microscope Chorion Yolk
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