Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / A Lab-On-A-Chip Platform for Stimulating…
JoVE Journal
Bioengineering

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto.

JoVE Journal Bioengineering
A Lab-On-A-Chip Platform for Stimulating Osteocyte Mechanotransduction and Analyzing Functional Outcomes of Bone Remodeling
Soybean Seed Sterilization (Video) | JoVE
Journal (Bioengineering)
Soybean Seed Sterilization (Video) | JoVE
Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids
Journal (Bioengineering)
Generation, High-Throughput Screening, and Biobanking of Human-Induced Pluripotent Stem Cell-Derived Cardiac Spheroids
 

A Lab-On-A-Chip Platform for Stimulating Osteocyte Mechanotransduction and Analyzing Functional Outcomes of Bone Remodeling

Article DOI: 10.3791/61076-v • 08:28 min • May 21st, 2020
May 21st, 2020 •
1, 1, 1, 1
1Department of Biomedical Engineering, The University of Akron

Capitoli

Riepilogo
Automatic Translation

Here, we present protocols for analyzing bone remodeling within a lab-on-a-chip platform. A 3D printed mechanical loading device can be paired with the platform to induce osteocyte mechanostransduction by deforming the cellular matrix. The platform can also be used to quantify bone remodeling functional outcomes from osteoclasts and osteoblasts (resorption/formation).

Tags

Lab-On-A-Chip Osteocyte Mechanotransduction Bone Remodeling Bone Cells Culturing Bone Formation Bone Resorption Mechanical Loading Environments Osteoporosis Fracture Healing Periprosthetic Osteolysis PDMS Prepolymer Curing Agent Microchannel Layer PDMS Membrane Layer
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter