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Journal / Neuroscience / Measuring Post-Stroke Cerebral Edema, Infarct…
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Neuroscience

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Measuring Post-Stroke Cerebral Edema, Infarct Zone and Blood-Brain Barrier Breakdown in a Single Set of Rodent Brain Samples

Article DOI: 10.3791/61309-v • 04:32 min • October 23rd, 2020
October 23rd, 2020 •
*1, *2, 1, 3, 4, 1, 1, 1, 1, 1
1Department of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 2Department of Anesthesiology, Yale University School of Medicine, 3Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, 4Department of Physiology, Faculty of Biology, Ecology and Medicine, Dnepropetrovsk State University
* These authors contributed equally

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This protocol describes a novel technique of measuring the three most important parameters of ischemic brain injury on the same set of rodent brain samples. Using only one brain sample is highly advantageous in terms of ethical and economic costs.

Tags

Post-stroke Cerebral Edema Infarct Zone Blood-brain Barrier Breakdown Rodent Brain Samples Middle Cerebral Artery Occlusion Technique Ischemic Brain Injury Infarct Zone Measurement Brain Edema Measurement BBB Permeability Measurement Ethical And Economic Costs Comprehensive Investigation Pathophysiology Of Ischemic Stroke Rat Brain Removal Horizontal Brain Sections TTC Incubation Optical Scanning Image Editing Blue Filter Application Hemispheric Selection Infarct Volume Calculation Brain Edema Calculation
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