Myocardial lactate production (coronary arterial-venous difference in serum lactate level) during coronary spasm provocation testing is considered as a highly sensitive marker that reflects acetylcholine-induced myocardial ischemia due to microvascular spasm. This article presents the procedures to assess myocardial lactate production for the diagnosis of coronary microvascular spasm.
Takahashi, J., Suda, A., Yasuda, S., Shimokawa, H. Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm. J. Vis. Exp. (175), e62558, doi:10.3791/62558 (2021).