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Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain

Article DOI: 10.3791/63667-v • 05:10 min • August 30th, 2022
August 30th, 2022 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,3, 1,2
1Department of Anatomy, Université du Québec à Trois-Rivières, 2CogNAC Research Group, Université du Québec à Trois-Rivières, 3Division of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz

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To develop novel therapeutic interventions for the prevention and management of back pain, animal models are required to examine the mechanisms and effectiveness of these therapies from a translational perspective. The present protocol describes the BMS test, a standardized method to assess back mechanical sensitivity in the rat.

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Mechanical Sensitivity Assessment Chronic Back Pain Rat Model Intervention Effectiveness Von Frey Test Hind Paw Assessment Behavioral Test Filaments Application Standardization Intramuscular Injection Complete Freund's Adjuvant (CFA) Back Muscles Injection Test Cage Fabrication
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