Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / Non-Invasive PET/MR Imaging in an Orthotopic…
JoVE Journal
Cancer Research

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto.

JoVE Journal Cancer Research
Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Journal (Cancer Research)
Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Isolation of Stem-like Cells from 3-Dimensional Spheroid Cultures
Journal (Cancer Research)
Isolation of Stem-like Cells from 3-Dimensional Spheroid Cultures
 

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Article DOI: 10.3791/63958-v • 07:47 min • August 31st, 2022
August 31st, 2022 •
*1,2, *3, 2, 1, 4, 1,5, 3
1Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 2Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, 3Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, 4Department of Biomedical Engineering, The Chinese University of Hong Kong, 5Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

Here, we present a protocol to create orthotopic hepatocellular carcinoma xenografts with and without hepatic artery ligation and perform non-invasive positron emission tomography (PET) imaging of tumor hypoxia using [18F]Fluoromisonidazole ([18F]FMISO) and [18F]Fluorodeoxyglucose ([18F]FDG).

Tags

Non-invasive PET/MR Imaging Orthotopic Mouse Model Hepatocellular Carcinoma Tumor Hypoxia HCC Biology Translational Research Real-time Monitoring Molecular Changes Tumor Aggressiveness Response To Treatment Intraabdominal Surgery Animal Care Small Animals Sterilize Dorsal Region Anesthetized Mouse Injection Needle Cell Suspension Subcutaneous Plane Syringe Contents Discharge Euthanizing Subcutaneous Tumor-bearing Mouse Incision Scalpel Blade Excise Tumor Block
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter