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Measurement of the Compressibility of Cell and Nucleus Based on Acoustofluidic Microdevice
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Measurement of the Compressibility of Cell and Nucleus Based on Acoustofluidic Microdevice

Article DOI: 10.3791/64225-v • 09:06 min • July 14th, 2022
July 14th, 2022 •
1, 1, 1, 1
1Sino-French Institute of Nuclear Engineering and Technology, Sun Yat-sen University

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Here a protocol is presented to build a fast and non-destructive system for measuring cell or nucleus compressibility based on acoustofluidic microdevice. Changes in mechanical properties of tumor cells after epithelial-mesenchymal transition or ionizing radiation were investigated, demonstrating the application prospect of this method in scientific research and clinical practice.

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Compressibility Acoustofluidic Microdevice Cell Mechanics Tumor Metastasis Malignant Transformation Radiosensitivity Measurement Suspended States Epithelial To Mesenchymal Transition Circulating Tumor Cells Cancer Diagnosis PDMS Block Chip Plasma Cleaner Bonding PTFE Catheter Stainless Steel Needle L Shape Inlet Deionized Water
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