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Assessment of Bone Fracture Healing Using Micro-Computed Tomography
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Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Article DOI: 10.3791/64262-v • 12:04 min • December 9th, 2022
December 9th, 2022 •
*1,2, *1,2, 1,2,3, 1,2, 1,2,4
1Center for Orthopaedic Research and Translational Science (CORTS), The Pennsylvania State University College of Medicine, 2Department of Orthopaedics and Rehabilitation, The Pennsylvania State University College of Medicine, 3Department of Pharmacology, The Pennsylvania State University College of Medicine, 4Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine
* These authors contributed equally

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Micro-computed tomography (µCT) is a non-destructive imaging tool that is instrumental in assessing bone structure in preclinical studies, however there is a lack of consensus on µCT procedures for analyzing the bone healing callus. This study provides a step-by-step µCT protocol that allows the monitoring of fracture healing.

Tags

Micro-Computed Tomography Bone Fracture Healing 3D Morphology Bone Quality Analysis Protocol Noninvasive Imaging Calibrated 3D Analysis Manual Techniques Automated Techniques Software Environment Scanning Fixture Bone Mineral Density Calibration Long Bone Samples Scanning Field Of View Preservative Micro-CT Machine Calibration Axial Direction Scanning Parameters
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