Name: Terapia di stimolazione magnetica transcranica personalizzata guidata da fMRI per depressione resistente al trattamento (Video) | JoVE Journal
Uploaded: 2026-04-10T12:43:00.000+00:00
Duration: 13 min 18 s
Description: Scopri la terapia TMS personalizzata guidata da fMRI per la depressione resistente, utilizzando connettività funzionale a riposo e consegna robotica per migliorare la precisione del targeting e gli esiti clinici.

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<li>George, M. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Eeg+synchronized+left+prefrontal+transcranial+magnetic+stimulation+%28tms%29+for+treatment+resistant+depression+is+feasible+and+produces+an+entrainment+dependent+clinical+response%3A+A+randomized+controlled+double+blind+clinical+trial%5BTitle%5D)+AND+%22Brain+Stimulat%22%5BJournal%5D)">Eeg synchronized left prefrontal transcranial magnetic stimulation (tms) for treatment resistant depression is feasible and produces an entrainment dependent clinical response: A randomized controlled double blind clinical trial.</a> Brain Stimulat. 16 (6), 1753-1763 (2023).</li>
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</ol>

<table><tbody><tr><td>Bobina Testa e Collo a 64 canali</td><td>Siemens</td><td>10606850</td><td></td></tr><tr><td>Servizio di calcolo nel cloud</td><td>Amazon</td><td>https://aws.amazon.com/?refid=536ef9fe-bc1d-4318-ae84-3df0523ed98a</td><td></td></tr><tr><td>Cobot</td><td>Axilum</td><td>https://www.axilumrobotics.com/en/</td><td>Questo cobot ha un'integrazione specifica di software e hardware con il sistema di neuronavigazione e la bobina.</td></tr><tr><td>DCM2NIIX</td><td>Rordern Lab</td><td>https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage; https://github.com/rordenlab/dcm2niix</td><td>Vedi https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage; https://github.com/rordenlab/dcm2niix per il manuale operativo. &nbsp;</td></tr><tr><td>fMRIPrep</td><td>NiPreps</td><td>https://fmriprep.org/en/stable/api.html</td><td>Strumento software open source per la pre-elaborazione della fMRI, vedi https://fmriprep.org/en/stable/ per il manuale operativo.</td></tr><tr><td>Macchina per risonanza magnetica</td><td>Siemens</td><td>166026</td><td>3 Tesla di intensità.</td></tr><tr><td>MRICron</td><td>NITRC</td><td>https://www.nitrc.org/projects/mricron</td><td>Strumento software open source per visualizzare immagini di risonanza magnetica, vedi https://www.nitrc.org/projects/mricron per il manuale operativo.</td></tr><tr><td>Telecamera di neuronavigazione</td><td>Northern Digital Inc.</td><td>P7-11191</td><td>Questa fotocamera di neuronavigazione, e altre della gamma dello stesso produttore &nbsp; sono compatibili con TMS Navigator</td></tr><tr><td>Bobina TMS</td><td>MagVenture</td><td>9016 E0151</td><td>Questa bobina è progettata per integrarsi hardware con il braccio robotico Cobot e viene dotata di un proprio sistema di raffreddamento.</td></tr><tr><td>Sistema di neuronavigazione TMS</td><td>Località</td><td>10225</td><td>Questo sistema di neuronavigazione dispone di funzioni software integrate specifiche con il cobot e lo stimolatore TMS.</td></tr><tr><td>Stimolatore TMS</td><td>MagVenture A/S</td><td>&nbsp; 9016E0721</td><td>Questo sistema di stimolazione TMS è progettato per integrarsi con la bobina e il sistema di neuronavigazione per il feedback di stimolazione (ad esempio, numero di impulsi, registrazione del potenziale evocato motorio).&nbsp;</td></tr></tbody></table>

terapia di stimolazione magnetica transcranica personalizzata guidata da fmri per depressione resistente al trattamento

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression

Terapia di stimolazione magnetica transcranica personalizzata guidata da fMRI per depressione resistente al trattamento

Improving the outcomes of transcranial magnetic stimulation (TMS) therapy for treatment-resistant depression may be achieved by personalizing the ...

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Fonte: Dunlop, K., et al. dmPFC-rTMS guidata dalla risonanza magnetica come trattamento per il disturbo depressivo maggiore resistente al trattamento. J. Vis. Exp. (2015)Questo video mostra la procedura per la stimolazione magnetica transcranica ripetitiva (rTMS) guidata dalla risonanza magnetica (rTMS) mirata alla corteccia prefrontale dorsomediale (dmPFC) per trattare la depressione.

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Qui vi presentiamo un protocollo che delinea la metodologia per il trattamento del disturbo depressivo maggiore utilizzando il sistema di profonda stimolazione magnetica transcranica (DTM).

Trattamento della depressione clinica con ripetitivo profonda stimolazione magnetica transcranica Utilizzando la Brainsway H1-coil

Il presente protocollo descrive l'applicazione della stimolazione magnetica transcranica ripetitiva (rTMS), in cui una sottoregione della corteccia prefrontale dorsolaterale (DLPFC) con la più forte anticorrelazione funzionale con la corteccia cingolata anteriore subgenuale (sgACC) è stata localizzata come bersaglio di stimolazione sotto l'assistenza di un sistema di neuronavigazione basato su fMRI.

Trattamento rTMS individualizzato per la depressione utilizzando un metodo di targeting basato su fMRI

Un nuovo protocollo per la stimolazione magnetica transcranica personalizzata in combinazione con la mappatura elettroencefalografica (TMS-EEG) delle reti corticali, informata da modalità di dati di risonanza magnetica multipla (MRI).

TMS-EEG guidato da neuroimaging per la mappatura della rete corticale in tempo reale

Questo protocollo presenta una guida per l'applicazione precisa e centrata sul paziente della stimolazione magnetica transcranica ripetitiva per la depressione maggiore resistente al trattamento. Vengono forniti dettagli sulle procedure per una localizzazione accurata della bobina, dosaggio regolabile dello stimolo, rigorose misure di sicurezza e strategie che massimizzino comfort, riproducibilità ed efficacia clinica a lungo termine durante sessioni acute e di mantenimento.

Stimolazione magnetica transcranica ripetitiva convenzionale per la depressione: un protocollo passo dopo passo

Fosfeni sono percezioni transitori di luce che può essere indotta mediante l'applicazione di Stimolazione Magnetica Transcranica (TMS) per le regioni della corteccia visiva sensibili. Dimostriamo un protocollo standard per la determinazione del valore di soglia fosfene e introdurre un nuovo metodo per quantificare ed analizzare fosfeni percepito.

Un nuovo approccio per documentare Fosfeni indotta dalla Stimolazione Magnetica Transcranica

In questo articolo prendiamo in esame la metodologia e le considerazioni rilevanti per la combinazione di TMS e fMRI per esaminare gli effetti della stimolazione cerebrale sulla rete di default.

La combinazione di stimolazione magnetica transcranica e fMRI per esaminare il modo predefinito della rete

In questo articolo esaminiamo gli effetti di dipendenza stato visivamente rilevanti TMS indotta presentazioni fosfenici movente.

Stato-dipendenza Effetti sulla TMS: uno sguardo al comportamento Motive fosfene

In questo articolo prendiamo in esame la metodologia e le considerazioni relative al protocollo di trattamento della depressione FDA ha approvato con il Neuronetics NeuroStar dispositivo TMS.

Il dispositivo TMS NeuroStar: Condurre la FDA ha approvato protocollo per il trattamento della depressione

Scopri la terapia TMS personalizzata guidata da fMRI per la depressione resistente, utilizzando connettività funzionale a riposo e consegna robotica per migliorare la precisione del targeting e gli esiti clinici.

Terapia di stimolazione magnetica transcranica personalizzata guidata da fMRI per depressione resistente al trattamento

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