Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish

Tamar E. Sztal; Avnika A. Ruparelia; Caitlin Williams; Robert J. Bryson-Richardson

doi:10.3791/54431

ジャーナル

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発生生物学

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ゼブラフィッシュで筋肉のパフォーマンスと機能を評価するためにタッチ誘発応答と歩行アッセイを使用して

Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish

JoVE Journal
発生生物学

This content is Free Access.

JoVE Journal 発生生物学

Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish

ゼブラフィッシュで筋肉のパフォーマンスと機能を評価するためにタッチ誘発応答と歩行アッセイを使用して

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12,751 Views

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09:40 min

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October 31, 2016

DOI:

10.3791/54431-v

DOI:

10.3791/54431-v

•

09:40 min

October 31, 2016

•

9 Views

Tamar E. Sztal*¹, Avnika A. Ruparelia*¹, Caitlin Williams¹, Robert J. Bryson-Richardson¹

¹School of Biological Sciences,Monash University

筆記録

概要

Zebrafish are an excellent model to study muscle function and disease. During early embryogenesis zebrafish begin regular muscle contractions producing rhythmic swimming behavior, which is altered when the muscle is disrupted. Here we describe a touch-evoked response and locomotion assay to examine swimming performance as a measure of muscle function.