4,806 Views
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08:21 min
October 26, 2020
DOI:
10.3791/61058-v
修正された2腎臓1クリップ(2K1C)ゴールドブラットマウスモデルは、腎動脈狭窄を開始し、レニン発現および腎臓損傷の増加を誘導するためにポリウレタンチューブを使用して開発された。ここでは、再現可能で一貫性のある2K1Cマウスモデルを生成するために、袖口を準備して腎動脈上に配置する詳細な手順について説明します。
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Saleem, M., Barturen-Larrea, P., Saavedra, L., Gomez, J. A. A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis. J. Vis. Exp. (164), e61058, doi:10.3791/61058 (2020).
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