全頭部オプトードアレイと短距離チャンネルを用いたfMRIとfNIRSの同時測定データ収集

Overview

This study presents a novel protocol for simultaneous collection of fMRI and fNIRS signals, allowing for improved alignment of data crucial in neuroimaging. The methodology has been tested with young adults and aims to be adaptable for use in clinical and developmental populations.

Key Study Components

Area of Science

• Neuroimaging
• Functional neuroimaging techniques
• Clinical neuroscience

Background

• fMRI is considered the gold standard in neuroimaging, providing insights into deeper brain structures.
• fNIRS is an emerging technique that can measure brain activity, albeit with limitations in depth.
• Previous attempts involved separate sessions for fMRI and fNIRS, which could influence participant response.
• Simultaneous recordings aim to enhance data interpretation, particularly in special populations.

Purpose of Study

• To develop a method for the simultaneous collection of fNIRS and fMRI data.
• To provide a reliable protocol adaptable for diverse populations, including those with neuropsychological deficits.
• To improve confidence in fNIRS signal interpretation through alignment with fMRI results.

Methods Used

• The study utilized simultaneous fMRI and fNIRS technology to gather brain imaging data.
• Key details included participant preparation, cap fitting, and the secure attachment of optodes for fNIRS.
• Participants underwent a scanning procedure involving careful setup and alignment to ensure comfort.
• 3D modeling of the head was performed to accurately place optodes before imaging.

Main Results

• Initial findings indicated increased activation in bilateral visual cortex areas during specific visual tasks.
• fNIRS data demonstrated a significant increase in HBO signal in response to stimuli, illustrating the method's effectiveness.
• The protocol showed promise for future research with clinical and developmental study participants.
• The methodology allows for reliable collection of neuroimaging data from participants who may have varying comfort levels with fMRI equipment.

Conclusions

• The developed protocol demonstrates the feasibility of collecting fMRI and fNIRS data simultaneously.
• The alignment of signals from both neuroimaging techniques enhances understanding of neural dynamics.
• This work has significant implications for research into neural networks in special populations.

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