Name: 分散度と末端基が異なる合成ポリマーの特性評価のためのMALDI-ToF MS法 (動画) | JoVE Journal
Uploaded: 2025-10-03T13:00:00.000+00:00
Duration: 6 min 16 s
Description: 学ぶMALDI-ToF MS法による合成ポリマーの特性評価。分散度と末端基が異なるサンプルの質量スペクトル解析、データ取得とキャリブレーションの詳細なプロトコルを解説。ポリマー構造と挙動の関係性を明らかにする手法です。

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</ol>

<table><tbody><tr><td>1-(3-ジメチルアミノプロピル)-3-エチルカルボジイミド塩酸塩</td><td>TCIケミカル</td><td>D1601</td><td>https://www.tcichemicals.com/US/en/p/D1601</td></tr><tr><td>1,1,1-トリス(ヒドロキシメチル)プロパン</td><td>ミリポアシグマ</td><td>148083</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/148083?srsltid=AfmBOoqaMzcy1xravp1h2QE 0myfY5gjuEBfOIv2o882Wb _xcB4Ol4CMW</td></tr><tr><td>1,5,7-トリアザビシクロ[4.4.0]dec-5-エン</td><td>ミリポアシグマ</td><td>345571</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/345571?srsltid=AfmBOooLQXIhWaMnO63nE xu-Y5MJoJID6RJiby0NXyu DHOxXYjle_kMT</td></tr><tr><td>1,6-ヘキサンジチオール 98% (HDT)&nbsp;</td><td>TCIの</td><td>H0334</td><td>https://www.tcichemicals.com/US/en/p/H0334</td></tr><tr><td>2-(4-ヒドロキシフェニルアゾ)安息香酸)(HABA)</td><td>ミリポアシグマ</td><td>H5126</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/h5126</td></tr><tr><td>2,2-ビス(ヒドロキシメチル)プロピオン酸</td><td>ミリポアシグマ</td><td>106615</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/106615?srsltid=AfmBOopCRoa1N_UiDK 56NKhDKdlAN8feUrMxVYhul Muz2en6NYEGIh4b</td></tr><tr><td>2,2-ジメトキシ-2-フェニルアセトフェノン 99% (DMPA)&nbsp;</td><td>シグマ・アルドリッチ</td><td>196118</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/196118?srsltid=AfmBOoqVTif6KNwIr6A -bIgnXbkrvWKIUNH6qOsc RseQLNVKi0DMWPb-</td></tr><tr><td>2,5-ジヒドロキシ安息香酸(DHB)</td><td>ミリポアシグマ</td><td>149357</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/149357</td></tr><tr><td>4-(ジメチルアミノ)ピリジン</td><td>ミリポアシグマ</td><td>522821</td><td>https://www.sigmaaldrich.com/US/en/search/522821?focus=products&page=1&perpage= 30&sort=relevance&用語=522821 &タイプ=製品&nbsp;</td></tr><tr><td>6-ブロモヘキサン酸</td><td>ミリポアシグマ</td><td>150452</td><td>https://www.sigmaaldrich.com/US/en/search/6-bromohexanoic-acid?focus=products&page=1 &perpage=30&sort=relevance&用語= 6-ブロモヘキサン酸%20酸&タイプ=製品&nbsp;</td></tr><tr><td>ベンズアルデヒドジメチルアセタール</td><td>ミリポアシグマ</td><td>226076</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/226076?srsltid= AfmBOorbjP7zD9MO3g5Xk LL3rNZ02PhfkXoRfe3EjRK7 TrqJ-kEOrTCN</td></tr><tr><td>安息香酸</td><td>ミリポアシグマ</td><td>242381</td><td>https://www.sigmaaldrich.com/US/en/product/sial/242381?srsltid=AfmBOook_iIcMnwuB3e _j-KetQyyHJ6Qq86jSK8 ZVxC3BorQgkO8Xg5I&nbsp;</td></tr><tr><td>ブルカー ウルトラフレクストリーム&nbsp;</td><td>ブルカーダルトニックス</td><td></td><td>https://www.bruker.com/en/products-and-solutions/mass-spectrometry/maldi-tof/ultraflextreme.html</td></tr><tr><td>クロロホルム</td><td>フィッシャーサイエンティフィック</td><td>AA32614K7</td><td>https://www.fishersci.com/shop/products/chloroform-acs-99-8-thermo-scientific/AA32614K7 ?searchHijack=true&searchTerm= クロロホルム-acs-99-8-thermo-scientific &searchType=Rapid&matchedCatNo =AA32614M6</td></tr><tr><td>ジスラノール、BP、98.5-101% (DT)</td><td>フィッシャーサイエンティフィック</td><td>18-602-270</td><td>https://www.fishersci.com/shop/products/dithranol-bp-98-5-101-spectrum-chemical/18602270</td></tr><tr><td>エチレンブラッシル酸塩</td><td>ミリポアシグマ</td><td>W354309</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/w354309?utm_source=google&utm_medium= CPC&utm_campaign=8692675663&utm _content=86098110623&gad_source= 1&gclid=CjwKCAiApY-7BhBjEiwAQMr rEdJTcKN5TEFkP1uHvRlVign3lwg2cj5 _spBUCrfi6exZ3Ur5sJkARxoCfWsQ AvD_BwE&nbsp;</td></tr><tr><td>ガルビノキシル、フリーラジカル</td><td>ミリポアシグマ</td><td>G307型</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/g307?srsltid= AfmBOopoWGDMXtLk5Erf0rVyl 7j442uyg8rIWkfBjhHZ2z0dDktH3y8-</td></tr><tr><td>メタノール</td><td>フィッシャーサイエンティフィック</td><td>A456</td><td>https://www.fishersci.com/shop/products/methanol-optima-lc-ms-grade-thermo-scientific/A4564</td></tr><tr><td>パラジウム、カーボンに10%、タイプ487、乾燥</td><td>フィッシャーサイエンティフィック</td><td>AAA1201206</td><td>https://www.fishersci.com/shop/products/palladium-10-carbon-type-487-dry-thermo-scientific-1/AAA1201206#?keyword=palladium%20on%20carbon</td></tr><tr><td>ポリ(エチレン&nbsp;グリコール)モノメチルエーテル350&NBSP;Mn&nbsp;(MeO-PEG-OH 360)&nbsp;</td><td>フィッシャーサイエンティフィック</td><td>AA4156022</td><td>https://www.fishersci.com/shop/products/polyethylene-glycol-monomethylether-350-thermo-scientific/AA4156022</td></tr><tr><td>トリフルオロ酢酸カリウム (KTFA)</td><td>ミリポアシグマ</td><td>281883</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/281883</td></tr><tr><td>プロパーギルアルコール</td><td>フィッシャーサイエンティフィック</td><td>A10295.0F</td><td>https://www.thermofisher.com/order/catalog/product/A10295.0F?SID=srch-hj-A10295.0F</td></tr><tr><td>臭化プロパーギル 97% (MgO で安定化したトルエン中 80% w/w)</td><td>フィッシャーサイエンティフィック</td><td>AAL1059514</td><td>https://www.fishersci.com/shop/products/propargyl-bromide-97-80-w-w-toluene-stab-magnesium-oxide-thermo-scientific/AAL1059514#?keyword=Propargyl%20bromide%2097%%20(80%%20w/w%20in%20トルエン%20安定化%20with%20MgO)</td></tr><tr><td>アジ化ナトリウム</td><td>ミリポアシグマ</td><td>S2002</td><td>https://www.sigmaaldrich.com/US/en/product/sial/s2002&nbsp;</td></tr><tr><td>水素化ナトリウム鉱物油に60%分散&nbsp;</td><td>ミリポアシグマ</td><td>452912</td><td>https://www.sigmaaldrich.com/US/en/product/aldrich/452912?srsltid= AfmBOooZhbCm_qtgKU99922Y91zI qEOWONlEGxjZn0mdSJF2L5hW1uVn</td></tr><tr><td>トリフルオロ酢酸ナトリウム(NaTFA)</td><td>オークウッド</td><td>MFCD00013217</td><td>https://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txt 検索=1549&ExtHyperLink=1</td></tr><tr><td>SpheriCal ニート ローレンジキット (250 - 7,500 Da)</td><td>ポリマーファクトリー</td><td>PFS-104</td><td>https://www.polymerfactory.com/product-page/spherical-low-range-kit-500-7-500-da</td></tr><tr><td>テトラヒドロフラン(THF)</td><td>フィッシャーサイエンティフィック</td><td>T427</td><td>https://www.fishersci.com/shop/products/tetrahydrofuran-optima-fisher-chemical-3/T4274#?keyword=tetrahydrofuran%20optima</td></tr><tr><td>トランス-2-[3-(4-tert-ブチルフェニル)-2-メチル-2-プロペニリデン]マロノニトリル(DCTB)</td><td>TCIの</td><td>B3635</td><td>https://www.tcichemicals.com/US/en/p/B3635</td></tr><tr><td>&α;-シアノ-4-ヒドロキシ桂皮酸(CHCA)</td><td>TCIの</td><td>1768年頃</td><td>https://www.tcichemicals.com/US/en/p/C1768</td></tr></tbody></table>

分散度と末端基が異なる合成ポリマーの特性評価のためのmaldi-tof ms法

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups

分散度と末端基が異なる合成ポリマーの特性評価のためのMALDI-ToF MS法

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS) is an effective analytical tool for characterizing synthetic ...

maldi-tof-ms-method-for-characterization-synthetic-polymers-with

Research

JoVE Journal

Chemistry

化学

迅速な方法は、細胞外マトリックス中の多糖類の構造についての洞察を得るために説明されています。方法はglycosylhydrolasesの特異性と材料の微量を分析できるように質量分析の感度を利用しています。この手法は、組織自体に直接使用するための適応です。...

細胞外多糖のオリゴマスプロファイリング（オリンプ）

ジスラノール（DT、1,8  - ジヒドロキシ-9,10  - ジヒドロアントラセン-9  - オン）は、以前に小分子の組織イメージングのためのMALDIマトリックスとして報告されている上に、内因性脂質​​のMALDIイメージングのためのDTの使用のためのプロトコル超高分解能四重極-FTICR機器上の正イオンMALDI-MSによる組織切片の表面は、ここで提供される。...

変換にマトリックス支援レーザー脱離/イオンイメージングのためのマトリックスとしてジスラノールはイオンサイクロトロン共鳴質量分析計をフーリエ

単一分子レベルでの環状ポリマーの拡散運動の合成と特性評価のためのプロトコルが提示されています。...

単一分子レベルでの環状ポリマーの合成と溶融状態におけるそれらの拡散運動のキャラクタリゼーション

所定の金属中心配列を含む水溶性多金属ペプチド配列の合成のための潜在的な一般的な方法が提示されます。...

水溶性有機金属錯体アレイの合成

ここで、我々は準備して二次構造を可視化するためのプロトコルを提示する（ 例えば 、繊維、トロイダルアーキテクチャ、およびナノ球体）ヘリカルポリカルボジイミド由来。両方の原子間力顕微鏡（AFM）及び走査電子顕微鏡（SEM）によって特徴付けられる形態は、分子構造、濃度、および選択した溶媒に依存することが示されました。...

ヘリカルポリカルボジイミド共重合体およびそれらのトリアゾール誘導体から得られた自己組み立てモルフォロジー

合成高分子の質量分析法 (MALDI-TOF MS)...

マトリクスによる合成高分子のキャラクタリゼーション支援レーザー脱離イオン化時間 (MALDI Tof) 質量分析装置

このプロトコルの目的は、溶媒を使用せずに穏やかな温度 (90 ° c) でポリ (ジビニルベンゼン) の動的硫黄結合を使用して重合を開始することです。Terpolymers は、GPC、DSC および 1h NMR...

ポリ (Terpolymers) における動的硫黄結合を用いた温暖な温度でのの合成

自己組織化金属有機フレームワーク単分子膜の合成および特性評価のためのプロトコルは、ポリマーグラフトされた金属有機フレームワーク(MOF)結晶を使用して提供されます。この手順は、ポリマーグラフトされたMOF粒子が空気-水界面で自己組織化され、走査型電子顕微鏡イメージングによって証明されるように、整形成された自立した単層構造が得られることを示しています。...

高分子被覆粒子を用いた自己組織化有機金属フレームワーク単分子膜の合成と評価

マトリックス支援レーザー脱離イオン化飛行時間型質量分析法を用いたペルメチル化ムチン O型糖鎖のプロファイリング

精密質量測定は、タンパク質の研究における重要なステップである。マトリックス支援レーザー脱離イオン化（MALDI）質量分析法（MS）は、そのような決定のために使用することができ、その主要な利点は、塩、界面活性剤および汚染に対する耐性である。ここでは、MALDI-MSによって100kDaのより大きなタンパク質の分析のためにアクセス可能なアプローチを示している。...

フライトのマトリックス支援レーザー脱離/イオン化飛行時間（MALDI-TOF）100kDaのより大きなインタクトタンパク質の質量分析

学ぶMALDI-ToF MS法による合成ポリマーの特性評価。分散度と末端基が異なるサンプルの質量スペクトル解析、データ取得とキャリブレーションの詳細なプロトコルを解説。ポリマー構造と挙動の関係性を明らかにする手法です。

分散度と末端基が異なる合成ポリマーの特性評価のためのMALDI-ToF MS法

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