Name: ラット足底屈筋の in vivo における 定荷重 (等張) および等速 (等速) トルク - 速度 - パワープロファイルの構築 (動画) | JoVE Journal
Uploaded: 2025-10-03T13:50:00.000+00:00
Duration: 7 min 44 s
Description: 学ぶラット足底屈筋のin vivoトルク・速度・パワー測定法。経皮的電気刺激を用いた非侵襲的プロトコルで、等張・等速収縮を評価し、筋機能と疾患影響を解析する。

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5 minutes

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<li>Dalton, B. H., Allen, M. D., Power, G. A., Vandervoort, A. A., Rice, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+effect+of+knee+joint+angle+on+plantar+flexor+power+in+young+and+old+men%5BTitle%5D)+AND+%22Exp+Gerontol%22%5BJournal%5D)">The effect of knee joint angle on plantar flexor power in young and old men.</a> Exp Gerontol. 52, 70-76 (2014).</li>
<li>Power, G. A., Dalton, B. H., Rice, C. L., Vandervoort, A. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Peak+power+is+reduced+following+lengthening+contractions+despite+a+maintenance+of+shortening+velocity%5BTitle%5D)+AND+%22Appl+Physiol+Nutr+Metab%22%5BJournal%5D)">Peak power is reduced following lengthening contractions despite a maintenance of shortening velocity.</a> Appl Physiol Nutr Metab. 38 (12), 1196-1205 (2013).</li>
<li>McNeil, C. J., Rice, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fatigability+is+increased+with+age+during+velocity-dependent+contractions+of+the+dorsiflexors%5BTitle%5D)+AND+%22J+Gerontol+A+Biol+Sci+Med+Sci%22%5BJournal%5D)">Fatigability is increased with age during velocity-dependent contractions of the dorsiflexors.</a> J Gerontol A Biol Sci Med Sci. 62 (6), 624-629 (2007).</li>
<li>Knight, K. L., Ingersoll, C. D., Bartholomew, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Isotonic+contractions+might+be+more+effective+than+isokinetic+contractions+in+developing+muscle+strength%5BTitle%5D)+AND+%22J+Sport+Rehabil%22%5BJournal%5D)">Isotonic contractions might be more effective than isokinetic contractions in developing muscle strength.</a> J Sport Rehabil. 10 (2), 124-131 (2001).</li>
<li>Thompson, B. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((It%E2%80%99s+time+to+re-evaluate+the+reporting+of+common+measures+from+isokinetic+dynamometers%3A+isokinetic+for+torque%2C+isotonic+for+power%5BTitle%5D)+AND+%22Front+Sports+Act+Living%22%5BJournal%5D)">It’s time to re-evaluate the reporting of common measures from isokinetic dynamometers: isokinetic for torque, isotonic for power.</a> Front Sports Act Living. 7, 1472712(2025).</li>
<li>Leeuwenburgh, C., Gurley, C. M., Strotman, B. A., Dupont-Versteegden, E. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+differences+in+apoptosis+with+disuse+atrophy+in+soleus+muscle%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Age-related differences in apoptosis with disuse atrophy in soleus muscle.</a> Am J Physiol Regul Integr Comp Physiol. 288 (5), R1288-R1296 (2005).</li>
<li>Padilla, C. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Profiling+age-related+muscle+weakness+and+wasting%3A+neuromuscular+junction+transmission+as+a+driver+of+age-related+physical+decline%5BTitle%5D)+AND+%22Geroscience%22%5BJournal%5D)">Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline.</a> Geroscience. 43 (3), 1265-1281 (2021).</li>
<li>Fuqua, J. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impaired+proteostatic+mechanisms+other+than+decreased+protein+synthesis+limit+old+skeletal+muscle+recovery+after+disuse+atrophy%5BTitle%5D)+AND+%22J+Cachexia+Sarcopenia+Muscle%22%5BJournal%5D)">Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy.</a> J Cachexia Sarcopenia Muscle. 14 (5), 2076-2089 (2023).</li>
<li>Ochi, E., Nakazato, K., Ishii, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+eccentric+exercise+on+joint+stiffness+and+muscle+connectin+%28titin%29+isoform+in+the+rat+hindlimb%5BTitle%5D)+AND+%22J+Physiol+Sci%22%5BJournal%5D)">Effects of eccentric exercise on joint stiffness and muscle connectin (titin) isoform in the rat hindlimb.</a> J Physiol Sci. 57 (1), 1-6 (2007).</li>
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<li>Herzog, W., Leonard, T. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Force+enhancement+following+stretching+of+skeletal+muscle%3A+a+new+mechanism%5BTitle%5D)+AND+%22J+Exp+Biol%22%5BJournal%5D)">Force enhancement following stretching of skeletal muscle: a new mechanism.</a> J Exp Biol. 205 (Pt 9), 1275-1283 (2002).</li>
<li>Lewis, M. T., Kasper, J. D., Bazil, J. N., Frisbee, J. C., Wiseman, R. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Skeletal+muscle+energetics+are+compromised+only+during+high-intensity+contractions+in+the+Goto-Kakizaki+rat+model+of+type+2+diabetes%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Skeletal muscle energetics are compromised only during high-intensity contractions in the Goto-Kakizaki rat model of type 2 diabetes.</a> Am J Physiol Regul Integr Comp Physiol. 317 (2), R356-R368 (2019).</li>
<li>Hill, C., James, R., Cox, V., Tallis, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Does+dietary-induced+obesity+in+old+age+impair+the+contractile+performance+of+isolated+mouse+soleus%2C+extensor+digitorum+longus+and+diaphragm+skeletal+muscles%5BTitle%5D)+AND+%22Nutrients%22%5BJournal%5D)">Does dietary-induced obesity in old age impair the contractile performance of isolated mouse soleus, extensor digitorum longus and diaphragm skeletal muscles.</a> Nutrients. 11 (3), 505(2019).</li>
<li>Yuan, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+atypical+%CE%B2-blocker+S-oxprenolol+reduces+cachexia+and+improves+survival+in+a+rat+cancer+cachexia+model%5BTitle%5D)+AND+%22J+Cachexia+Sarcopenia+Muscle%22%5BJournal%5D)">The atypical β-blocker S-oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model.</a> J Cachexia Sarcopenia Muscle. 14 (1), 653-660 (2023).</li>
<li>Hinks, A., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+differences+in+the+loss+and+recovery+of+serial+sarcomere+number+following+disuse+atrophy+in+rats%5BTitle%5D)+AND+%22Skeletal+Muscle%22%5BJournal%5D)">Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats.</a> Skeletal Muscle. 14 (1), 18(2024).</li>
<li>Hulst, J. B., Minamoto, V. B., Lim, M. B., Bremner, S. N., Ward, S. R., Lieber, R. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Systematic+test+of+neurotoxin+dose+and+volume+on+muscle+function+in+a+rat+model%5BTitle%5D)+AND+%22Muscle+Nerve%22%5BJournal%5D)">Systematic test of neurotoxin dose and volume on muscle function in a rat model.</a> Muscle Nerve. 49 (5), 709-715 (2014).</li>
<li>Wang, X., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Human+neural+stem+cells+transplanted+during+the+sequelae+phase+alleviate+motor+deficits+in+a+rat+model+of+cerebral+palsy%5BTitle%5D)+AND+%22Cytotherapy%22%5BJournal%5D)">Human neural stem cells transplanted during the sequelae phase alleviate motor deficits in a rat model of cerebral palsy.</a> Cytotherapy. 26 (12), 1491-1504 (2024).</li>
<li>Baltgalvis, K. A., Call, J. A., Cochrane, G. D., Laker, R. C., Yan, Z., Lowe, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Exercise+training+improves+plantar+flexor+muscle+function+in+mdx+mice%5BTitle%5D)+AND+%22Med+Sci+Sports+Exerc%22%5BJournal%5D)">Exercise training improves plantar flexor muscle function in mdx mice.</a> Med Sci Sports Exerc. 44 (9), 1671-1679 (2012).</li>
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<li>Mintz, E. L., Passipieri, J. A., Lovell, D. Y., Christ, G. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Applications+of+in+vivo+functional+testing+of+the+rat+tibialis+anterior+for+evaluating+tissue+engineered+skeletal+muscle+repair%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Applications of in vivo functional testing of the rat tibialis anterior for evaluating tissue engineered skeletal muscle repair.</a> J Vis Exp. (116), e54487(2016).</li>
<li>Song, H., Nakazato, K., Nakajima, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effect+of+increased+excursion+of+the+ankle+on+the+severity+of+acute+eccentric+contraction-induced+strain+injury+in+the+gastrocnemius%3A+an+in+vivo+rat+study%5BTitle%5D)+AND+%22Am+J+Sports+Med%22%5BJournal%5D)">Effect of increased excursion of the ankle on the severity of acute eccentric contraction-induced strain injury in the gastrocnemius: an in vivo rat study.</a> Am J Sports Med. 32 (5), 1263-1269 (2004).</li>
<li>Hinks, A., Patterson, M. A., Njai, B. S., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+blunting+of+serial+sarcomerogenesis+and+mechanical+adaptations+following+4+weeks+of+maximal+eccentric+resistance+training%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 weeks of maximal eccentric resistance training.</a> J Appl Physiol. 136 (5), 1209-1225 (2024).</li>
<li>Hinks, A. A., Vlemmix, E., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Submaximal+eccentric+resistance+training+increases+serial+sarcomere+number+and+improves+dynamic+muscle+performance+in+old+rats%5BTitle%5D)+AND+%22Physiol+Rep%22%5BJournal%5D)">Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats.</a> Physiol Rep. 12 (19), e70036(2024).</li>
<li>Hinks, A., Vlemmix, E., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Submaximal+eccentric+training+during+immobilization+does+not+prevent+serial+sarcomere+loss+or+impairments+in+mechanical+function+in+old+or+young+rats%5BTitle%5D)+AND+%22J+Gerontol+A+Biol+Sci+Med+Sci%22%5BJournal%5D)">Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats.</a> J Gerontol A Biol Sci Med Sci. 80 (7), glaf082(2025).</li>
<li>Vlemmix, E., Hinks, A., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Serial+sarcomerogenesis+does+not+contribute+to+the+initial+repeated+bout+effect+in+skeletal+muscle%5BTitle%5D)+AND+%22J+Biomech%22%5BJournal%5D)">Serial sarcomerogenesis does not contribute to the initial repeated bout effect in skeletal muscle.</a> J Biomech. 187, 112767(2025).</li>
<li>Oh, S. S., Narver, H. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mouse+and+rat+anesthesia+and+analgesia%5BTitle%5D)+AND+%22Curr+Protoc%22%5BJournal%5D)">Mouse and rat anesthesia and analgesia.</a> Curr Protoc. 4 (2), e995(2024).</li>
<li>Paris, M. T., McNeil, C. J., Power, G. A., Rice, C. L., Dalton, B. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+performance+fatigability%3A+a+comprehensive+review+of+dynamic+tasks%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Age-related performance fatigability: a comprehensive review of dynamic tasks.</a> J Appl Physiol. 133 (4), 850-866 (2022).</li>
<li>Hinks, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Time+course+changes+in+in+vivo+muscle+mechanical+function+and+Ca2%2B+regulation+of+force+following+experimentally+induced+gradual+ovarian+failure+in+mice%5BTitle%5D)+AND+%22Exp+Physiol%22%5BJournal%5D)">Time course changes in in vivo muscle mechanical function and Ca2+ regulation of force following experimentally induced gradual ovarian failure in mice.</a> Exp Physiol. 109 (5), 711-728 (2024).</li>
<li>Edman, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Double-hyperbolic+force-velocity+relation+in+frog+muscle+fibres%5BTitle%5D)+AND+%22J+Physiol%22%5BJournal%5D)">Double-hyperbolic force-velocity relation in frog muscle fibres.</a> J Physiol. 404 (1), 301-321 (1988).</li>
</ol>

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ラット足底屈筋の in vivo における 定荷重 (等張) および等速 (等速) トルク - 速度 - パワープロファイルの構築

Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors

Understanding the torque-velocity-power relationship of muscle is critical for assessing dynamic muscle performance, which has implications for health and ...

construction-constant-load-isotonic-constant-velocity-isokinetic

Research

JoVE Journal

Bioengineering

バイオエンジニアリング（生体工学）

私たちは、犬の後肢の筋肉の強さと繰り返しエキセントリック収縮に対する筋肉の反応を測定するために低侵襲かつ無痛の方法を説明します。...

ビボ犬筋肉の機能アッセイに

アン in vivoで</em収縮で誘起された損傷と回復の非侵襲的モニタリングの>齧歯類モデル

このビデオでは、外科的な準備やラット内側腓腹筋の筋標本の収縮反応を研究するために必要な手順を示しています...

ラットのための手順<em&gt;その場で</em&gt;骨格筋収縮特性

神経筋機能の変化を評価するためのプロトコルを提示します。経皮的電気神経刺激は、筋肉の反応を呼び起こす非侵襲的な方法です。これらの応答の電気生理学的および機械的特性により、脳から筋肉への神経筋機能(脊髄上、脊髄、末梢レベル)の評価が可能になります。...

経皮的電気神経刺激を使用した神経筋機能の評価

私たちは、腓骨神経の刺激とラットの後肢の前腓コンパートメントの収縮に続く足の背屈を測定するためのin...

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ラットにおける脛表筋前筋の最大等角体テタニック力測定

加齢、病気、傷害、およびリハビリテーションに対する機能的適応を理解するためには、膝伸筋の最大強度の定量化が不可欠である。生体内膝伸張等角値ピークテタニクトルクを繰り返し測定する新しい方法を紹介する。...

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使いすぎ誘発性腱鞘炎の in vivo モデルのための受動的足関節背屈試験システム

学ぶラット足底屈筋のin vivoトルク・速度・パワー測定法。経皮的電気刺激を用いた非侵襲的プロトコルで、等張・等速収縮を評価し、筋機能と疾患影響を解析する。

ラット足底屈筋の in vivo における定荷重 (等張) および等速 (等速) トルク - 速度 - パワープロファイルの構築

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ラット足底屈筋の in vivo における 定荷重 (等張) および等速 (等速) トルク - 速度 - パワープロファイルの構築

さらに動画を探す

ラット足底屈筋の in vivo における定荷重 (等張) および等速 (等速) トルク - 速度 - パワープロファイルの構築