Using Chick Embryo Brain as a Model to Study Human Glioblastoma Cell Behavior

May 26th, 2023

Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior (Video) | JoVE

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Nicole G. Pastorino¹, Saori Tomatsu¹, Amy Lin¹, Jackson Doerr¹, Zachary Waterman¹, Krisztina Sershen¹, Pulak Ray², Analiz Rodriguez³, Deni S. Galileo¹

¹Department of Biological Sciences, University of Delaware, ²Helen F. Graham Cancer Center and Research Institute, Christiana Care, ³Department of Neurosurgery, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences

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Kükenembryonen werden zur Untersuchung von humanen Glioblastom-Hirntumoren (GBM) in ovo - und in ex vivo-Hirnschnitt-Kokulturen verwendet. Das Verhalten von GBM-Zellen kann durch Zeitraffermikroskopie in ex vivo Kokulturen aufgezeichnet werden, und beide Präparate können am experimentellen Endpunkt durch detaillierte konfokale 3D-Analyse analysiert werden.

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Using Chick Embryo Brain as a Model to Study Human Glioblastoma Cell Behavior

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