고혈압 I: 서론

Hypertension is characterized by systolic pressure of 130 mmHg or higher or diastolic pressure exceeding 80 mmHg. These thresholds distinguish hypertension from normal blood pressure and guide clinical diagnosis. Blood pressure classification helps healthcare providers determine appropriate intervention strategies for managing this chronic arterial condition.

Primary hypertension has no identifiable cause but involves genetic and environmental factors like sodium intake, sedentary lifestyle, and tobacco use. Secondary hypertension, accounting for 5-10% of cases, results from identifiable underlying conditions such as left ventricular hypertrophy or coronary artery disease. Secondary hypertension requires thorough investigation, especially in sudden onset or drug-resistant cases.

Primary hypertension is influenced by high sodium intake, obesity, sedentary lifestyle, aging, genetic predisposition, ethnicity, tobacco use, excessive alcohol consumption, and diabetes. Changes in endothelial function and increased sympathetic nervous system activity also play roles. These modifiable and non-modifiable factors create a complex interplay affecting blood vessel regulation and pressure elevation.

Stage 1 hypertension is marked by systolic pressure between 130 and 139 mmHg or diastolic pressure between 80 and 89 mmHg. This classification requires lifestyle modification and, in some cases, medication to manage blood pressure levels effectively. Stage 1 represents an intermediate severity requiring intervention to prevent progression to stage 2.

Elevated blood pressure, indicated by systolic pressure between 120 and 129 mmHg with diastolic pressure below 80 mmHg, serves as a critical alert stage signaling the need for lifestyle modifications. This classification helps prevent hypertension progression before it reaches stage 1 or stage 2 severity. Early intervention at this stage can reduce future cardiovascular complications.

Excessive target organ damage signals secondary hypertension and may include cerebral vascular disease, retinopathy, chronic kidney disease, left ventricular hypertrophy, coronary artery disease, or peripheral arterial disease. These conditions warrant investigation to identify underlying causes. Understanding these manifestations helps clinicians recognize when hypertension stems from identifiable medical conditions requiring specific treatment approaches.

A hypertensive crisis occurs when systolic pressure exceeds 180 mmHg and/or diastolic pressure exceeds 120 mmHg, requiring immediate medical attention. This severe elevation poses acute risk for organ damage and cardiovascular complications. Hypertensive crisis represents the most severe classification and demands urgent intervention to prevent life-threatening consequences.