Erratum: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease

DOI:

10.3791/6500

2022년 5월 20일

이 논문에서

요약

Loading...
$$\rightleftharpoonup{xx}$$ $$\longleftharp{xx}$$, $$\longrightharp{xx}$$,

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

초록

Loading...
$$\rightleftharpoonup{xx}$$ $$\longleftharp{xx}$$, $$\longrightharp{xx}$$,

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

The first sentence of the Introduction was updated from:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,00,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

to:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,000,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

Step 1.3 in the Protocol was updated from:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol was used.

to:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol/saline was used.

프로토콜

Loading...
$$\rightleftharpoonup{xx}$$ $$\longleftharp{xx}$$, $$\longrightharp{xx}$$,

An erratum was issued for: A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease. The Introduction and Protocol were updated.

The first sentence of the Introduction was updated from:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,00,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

to:

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) are chronic inflammatory disorders of the gastrointestinal tract affecting approximately 20 per 1,000,000 in Europe and USA. CD is characterized by transmural inflammation, intestinal fibrosis, and luminal stenosis.

Step 1.3 in the Protocol was updated from:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol was used.

to:

Prepare fresh TNBS solution according to body weights.
NOTE: TNBS - 65 mg/kg of body weight in 250 µL of 40% ethanol/saline was used.

공개 사항

Loading...
$$\rightleftharpoonup{xx}$$ $$\longleftharp{xx}$$, $$\longrightharp{xx}$$,
No conflicts of interest declared.

재인쇄 및 허가

이 JoVE 논문의 텍스트 또는 그림 재사용 허가 요청

허가 요청

태그

Crohns Disease ModelTNBS Induced ColitisMechanical Stress PathogenesisRodent IBD ModelInflammatory Bowel DiseaseTNBS Solution PreparationEthanol Saline MixtureBody Weight DosingGastrointestinal Tract InflammationTransmural Inflammation Analysis