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Immunology and Infection

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Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches

Article DOI: 10.3791/51055-v • 09:04 min • October 27th, 2013
October 27th, 2013 •
1, 1, 1, 1
1Institute of Microbiology, University Hospital Center and University of Lausanne

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요약
Automatic Translation

Amoebal coculture is a cell culture system using adherent amoebae to selectively grow intracellular pathogens able to resist phagocytic cells such as amoebae and macrophages. It thus represents a key tool to discover new infectious agents. Amoebal enrichment allows discovery of new amoebal species and of their specific intracellular bacteria.

Tags

Intracellular Pathogens Legionella Mycobacteria Chlamydia-like Organisms Amoebae Host-cell Bacterial Isolation Amoebal Coculture Amoebal Enrichment Clinical Samples Environmental Samples Intracellular Bacteria Amoebal Species Phagocytosis Pathogenic
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