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Immunology and Infection

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Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice

Article DOI: 10.3791/51724-v • 06:48 min • July 25th, 2014
July 25th, 2014 •
*1, *1, 1
1Department of Biomedicine, Immunoregulation, University of Basel and University Hospital Basel
* These authors contributed equally

챕터

요약
Automatic Translation

Tail-skin transplantation is a powerful model for studying T cell-dependent rejection and tolerance induction during allogeneic immune responses in mice. The advantages of this protocol are minor invasive surgery, and ease of monitoring with no need to sacrifice the recipient mouse.

Tags

Tail-skin Transplantation Allogeneic CD4 T Cell Responses Mice Model Graft Rejection Immunological Questions Major Histocompatibility Antigens Allograft Rejection Activating Allogeneic T Cells MHC Class I And II Molecules Antigen-presenting Groove
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