Olfactory Assays for Mouse Models of Neurodegenerative Disease

Andrew M. Lehmkuhl; Emily R. Dirr; Sheila M. Fleming

doi:10.3791/51804

Journal

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신경과학

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신경 퇴행성 질환의 마우스 모델에 대한 후각 분석 실험

Olfactory Assays for Mouse Models of Neurodegenerative Disease

JoVE 신문
신경과학

This content is Free Access.

JoVE 신문 신경과학

Olfactory Assays for Mouse Models of Neurodegenerative Disease

신경 퇴행성 질환의 마우스 모델에 대한 후각 분석 실험

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21,897 Views

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07:27 min

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August 25, 2014

DOI:

10.3791/51804-v

DOI:

10.3791/51804-v

•

07:27 min

August 25, 2014

•

13 Views

Andrew M. Lehmkuhl¹, Emily R. Dirr^2,3, Sheila M. Fleming^1,2

¹Department of Psychology,University of Cincinnati, ²Department of Neurology,University of Cincinnati, ³Department of Neuroscience, Cell Biology, and Physiology,Wright State University

Summary

Impairment in olfactory function is a common feature in many neurodegenerative disorders including Parkinson, Alzheimer, and Huntington diseases. In the present article, we describe a set of tests for assessing olfaction discrimination and detection in mice that can be used to measure olfactory abilities in mouse models of neurodegenerative diseases.