Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

Joely D. Jacobs; Elizabeth A. Hopper-Borge

doi:10.3791/51917

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Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

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Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

22,814 Views

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08:41 min

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October 27, 2014

DOI:

10.3791/51917-v

DOI:

10.3791/51917-v

•

08:41 min

October 27, 2014

•

3 Views

Joely D. Jacobs¹, Elizabeth A. Hopper-Borge¹

¹Program in Developmental Therapeutics,Fox Chase Cancer Center

Summary

This method was developed with the goal of delivering a steady drug solution via the carotid artery, to assess the pharmacokinetics of novel drugs in mouse models.

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Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

Summary

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