Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / The Multi-organ Chip - A Microfluidic Platform…
JoVE Journal
Bioengineering

이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.

JoVE Journal Bioengineering
The Multi-organ Chip - A Microfluidic Platform for Long-term Multi-tissue Coculture
Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
Journal (Bioengineering)
Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
Journal (Bioengineering)
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
 

The Multi-organ Chip - A Microfluidic Platform for Long-term Multi-tissue Coculture

Article DOI: 10.3791/52526-v • 10:05 min • April 28th, 2015
April 28th, 2015 •
*1, *1,2, 1, 1,2, 1, 3, 3, 1, 1,2
1Medical Biotechnology, Technische Universität Berlin, 2TissUse GmbH, 3Fraunhofer IWS
* These authors contributed equally

챕터

요약
Automatic Translation

Here, we present a protocol to coculture primary cells, tissue models and punch biopsies in a microfluidic multi-organ chip for up to 28 days. Human dermal microvascular endothelial cells, liver aggregates and skin biopsies were successfully combined in a common media circulation.

Tags

Multi-organ Chip Microfluidic Platform Long-term Multi-tissue Coculture Substance Testing In Vitro Test Systems Drug-induced Liver Injury Microenvironment Multiple Dosing Experiments Extracellular Conditions Microengineered Bioreactor On-chip Pump Culture Spaces Circulatory System Primary Cell Cultures Human Liver Equivalents HepaRG Cells Hepatic Stellate Cells Hanging Drop Plates Human Skin Punch Biopsies Microbioreactor System
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter